Malignant Glomus Tumor of the Heart in a 64-Year Old Male Presenting with Stroke

Abstract

Glomus tumor is a soft tissue neoplasm usually observed as a solitary, or sometimes multicentric painful mass, that rarely occurs extracutaneously. We describe a rare case of malignant glomus tumor of the heart in a 64-year-old male diagnosed with a left ventricular mass. Echocardiography and color flow Doppler revealed a large echogenic mobile structure in the left ventricular cavity that was surgically resected. The histopathologic diagnosis was malignant cardiac glomus tumor. We describe the histopathology, differential diagnosis and clinical presentation of this extremely rare primary cardiac tumor.

What Is Hidden Behind Inferior Negative T Waves

“…They also do not stain for neuroendocrine markers such as synaptophysin, chromogranin, and S100. The differential diagnosis between glomus tumors and other smooth muscle tumors relies on clinical presentation and specific histological features ( 1 , 5 ).…”

An unusual case of chest wall glomus tumor presenting with axillary pain: a case report and literature review

“…The GTs can be found in any location, even in visceral organs. There are reported cases of GT affecting breast [ 18 ], thyroid [ 6 , 10 ], heart [ 7 , 19 ], trachea [ 2 , 20 ], lung [ 8 ], mediastinum [ 21 , 22 ], esophagus [ 5 , 23 ], stomach [ 24 , 25 ], liver [ 26 ], small intestine [ 9 ] and colon [ 27 ]. Extra-digital cases may be missed frequently as a result of affecting less common sites and their atypical presentation.…”

An Unusual Case of chest wall Glomus Tumor presenting with axillary pain: a case report and literature review

“…The GTs can be found in any location, even in visceral organs. There are reported cases of GT affecting breast (18), thyroid(6, 10), heart (7,19), trachea (2,20), lung(8), mediastinum (21,22), esophagus(5, 23), stomach (24,25), liver(26), small intestine(9) and colon (27). Extra-digital cases may be missed frequently as a result of affecting less common sites and their atypical presentation.…”

“…The lesion is mostly benign, and its excision has a cure rate of around 90 percent (4). However, malignant (5)(6)(7)(8)(9) and even lethal varieties (8,10) also are described in the literature.…”