“Malignant Granular Cell Tumour  Presenting as a Paravertebral Mass  in an Adolescent Male- A Rare  Presentation of an Uncommon Tumour”

Singh, Monika; Singh, Ajay; Shubham, Swasti; Maan, Pratibha; Chauhan, Udit

doi:10.7860/jcdr/2017/17928.9223

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…However, both benign and malignant GCT, have been found in a wide variety of other locations, including skin, heart, lung, abdominal wall, etc. [3]. Characteristic histological appearance of GCT is the presence of large polygonal cells with finely granular, abundant, eosinophilic cytoplasm.…”

Section: Introductionmentioning

confidence: 99%

“…Six morphological criteria for diagnosis of malignant GCT as suggested by this group include spindling of tumour cells, increased nuclear to cytoplasmic ratio, nuclear pleomorphism, necrosis, vesicular nuclei with large nucleoli and increased mitotic activity (>2 mitoses per 10 high-powered fields). GCT that meets three or more of these criteria are classified as malignant, whereas tumours showing one or two criteria are classified as atypical while benign ones display only focal pleomorphism if any [3,4].…”

Section: Introductionmentioning

confidence: 99%

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Malignant Granular Cell Tumour of the Thigh with Lung Metastases in a Young Woman; A Rare Presentation

Hiroshini¹,

Vithanage²

2019

J Diagnostic Path

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Granular Cell Tumour (GCT) is an uncommon soft tissue neoplasm. Majority of GCT are benign involving the soft tissue of the head and neck region. However, few show malignant behaviour with local recurrence and distant metastases often involving the lower extremities. Here we report a rare case of malignant granular cell tumour in a 33year-old woman involving the left thigh with regional lymph node and multiple lung metastases.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Malignant Granular Cell Tumour of the Thigh with Lung Metastases in a Young Woman; A Rare Presentation

Hiroshini¹,

Vithanage²

2019

J Diagnostic Path

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Malignant granular cell tumor of the median nerve: a case report with a literature review of 157 cases

et al. 2018

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Malignant granular cell tumors are an extremely rare, high-grade sarcoma with a schwannian phenotype and are composed of malignant granular cells with cytoplasmic lysosomal inclusion. To date, 157 cases of malignant granular cell tumors have been reported. We report the first case of a malignant granular cell tumor arising from the digital nerve to the median nerve in the palm, and we review the 157 previously reported cases and summarize the clinical profile, treatment, and outcome of this tumor. The median age, tumor size, and follow-up periods were 51 years, 6 cm, and 24 months respectively. With respect to the oncological result, 53 patients (33.8%) had no evidence for disease, 31 (19.7%) were alive with the disease, and 51 (32.5%) died because of the disease. Our case report indicates that rare malignant tumors can arise from the digital nerve to the median nerve in the palm, an anatomical site that is usually affected by benign lesions. Exhaustive discussions between surgeons and pathologists are necessary for the treatment of this rare malignant tumor.

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“Malignant Granular Cell Tumour Presenting as a Paravertebral Mass in an Adolescent Male- A Rare Presentation of an Uncommon Tumour”

Cited by 2 publications

References 5 publications

Malignant Granular Cell Tumour of the Thigh with Lung Metastases in a Young Woman; A Rare Presentation

Malignant Granular Cell Tumour of the Thigh with Lung Metastases in a Young Woman; A Rare Presentation

Malignant granular cell tumor of the median nerve: a case report with a literature review of 157 cases

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