Malignant hemangiopericytoma of the liver: Report of a case

Abstract

A 30 year old female was admitted with right upper abdominal pain and fever. Ultrasonography and computed tomography revealed a large cystic mass in the right lobe of the liver, and aspiration bacteriology was negative. A right hepatic lobectomy was performed for a suspected cystadenocarcinoma, however, the tumor was histologically diagnosed as a hemangiopericytoma with prominent venous invasion. The patient died within a short time of multiple pulmonary metastases. Primary hepatic hemangiopericytoma is extremely rare, and according to our research, this is only the 4th case reported in the literature.

Primary hemangiopericytoma of the liver: Sonographic findings

“…1,2,4 HP originating from a proliferation of capillaries and spindle-shaped cells can develop in any part of the body in which capillaries are present. [1][2][3][4][5] At the gross examination, HP appears in most cases as a single lesion, usually more than 5 cm in diameter at the diagnosis when the tumor originates in the liver, delimited by a capsule, highly vascularized, and with large areas of hemorrhagic and cystic degeneration separated by vascularized septa. [1][2][3][4][5] On unenhanced sonography, HP may appear as a solid (hyperechoic), cystic (hypoechoic), or complex mass, depending on the amount of cystic and hemorrhagic degeneration.…”

“…Differential diagnosis includes any other hypervascular hepatic primary neoplasms. 1,2,4,5 Solitary fibrous tumor of the liver is very rare (only 23 cases described), usually well circumscribed and highly vascularized with delayed venous washing-out. Cystic or necrotic areas are usually not present; histologically, both the tumors are similar.…”

“…P rimary hemangiopericytoma (HP) of the liver is a very rare tumor, and only 8 cases have been reported in the literature worldwide. [1][2][3][4][5][6] The neoplasm can be clinically silent or cause a paraneoplastic syndrome, such as hypoglycemia or hypertension. It is usually identified during a sonography screening, appearing as a large inhomogeneous mass.…”

Liver Recurrence of a Subcutaneous Temporal Hemangiopericytoma: The Index Case

“…3 Although liver parenchyma is rarely affected, few cases of either primary or metastatic location have been reported. [4][5][6][7][8][9][10][11] We herein report the first case of a subcutaneous temporal hemangiopericytoma that presented three consecutive local recurrences and, 14 years after the initial diagnosis and 3 years after the last local recurrence, a liver recurrence.…”