Malignant Melanoma Incidence at the Los Alamos National Laboratory

Acquavella, J.F.; Wilkinson, Gregg S.; Tietjen, Gary L.; Key, C R; Voelz, G.L.

doi:10.1016/s0140-6736(82)92153-5

Cited by 41 publications

(7 citation statements)

References 3 publications

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“…Excess skin cancer mortality has been noted for radiologists [Metanoski et al, 1975] and for employees of a nuclear fuels fabricating plant [Hadjimichael et al, 1983]. Conversely, in an analyses of data from existing records and using a slightly different study design, Acquavella et al [1982] found no overall excess of malignant melanoma among employees at Los Alamos National Laboratory (LANL).…”

Section: Discussionmentioning

confidence: 99%

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part II–nested case‐control study

Shaham¹,

Gurvich²,

Kneshet³

2003

American J Industrial Med

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Section: Discussionmentioning

confidence: 99%

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part II–nested case‐control study

Shaham¹,

Gurvich²,

Kneshet³

2003

American J Industrial Med

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“…The authors of that study describe matches on several exposure related variables, which may have influenced their results. From the radiation laboratory at Los Alamos, which had similar activities as LLNL, an incidence study based on six cases 27 and a case-control study with 15 male and 5 female cases 28 have been published. These studies 27 28 have not found a clear association between radiation and the risk of malignant melanoma.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for cutaneous malignant melanoma among aircrews and a random sample of the population

Rafnsson

Hrafnkelsson²,

Tulinius³

et al. 2003

Occup Environ Med

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Aims: To evaluate whether a difference in the prevalence of risk factors for malignant melanoma in a random sample of the population and among pilots and cabin attendants could explain the increased incidence of malignant melanoma which had been found in previous studies of aircrews. Methods: A questionnaire was used to collect information on hair colour, eye colour, freckles, number of naevi, family history of skin cancer and naevi, skin type, history of sunburn, sunbed, all sunscreen use, and number of sunny vacations. Results: The 239 pilots were all males and there were 856 female cabin attendants, which were compared with 454 males and 1464 females of the same age drawn randomly from the general population. The difference in constitutional and behavioural risk factors for malignant melanoma between the aircrews and the population sample was not substantial. The aircrews had more often used sunscreen and had taken more sunny vacations than the other men and women. The predictive values for use of sunscreen were 0.88 for pilots and 0.85 for cabin attendants and the predictive values for sunny vacation were 1.36 and 1.34 respectively. Conclusion: There was no substantial difference between the aircrew and the random sample of the population with respect to prevalence of risk factors for malignant melanoma. Thus it is unlikely that the increased incidence of malignant melanoma found in previous studies of pilots and cabin attendants can be solely explained by excessive sun exposure.

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“…This factor was not significant in the in situ case-control pairs. When consideration was restricted to LLNL employment, 18 cases had higher scores for the Nevada Test Site than their matched controls. This was compared to nine pairs where the confrol had a higher score.…”

Section: Occupational Interview Resultsmentioning

confidence: 96%

Workplace investigation of increased diagnosis of malignant melanoma among employees of Lawrence Livermore National Laboratory

Moore¹,

Patterson²,

Hatch³

et al. 1994

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Malignant Melanoma Incidence at the Los Alamos National Laboratory

Cited by 41 publications

References 3 publications

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part II–nested case‐control study

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part II–nested case‐control study

Risk factors for cutaneous malignant melanoma among aircrews and a random sample of the population

Workplace investigation of increased diagnosis of malignant melanoma among employees of Lawrence Livermore National Laboratory

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