Malignant melanoma maxilla

Devi, Seema; Sinha, Richi; Singh, Rakesh Kumar

doi:10.4103/0975-5950.168216

Cited by 6 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Percentage of different histological grades among SCC are well differentiated SCC 83.3% (10 out of 12 cases of SCC), moderately differentiated SCC and poorly differentiated SCC 8.3% each (1 each out of 12 cases of SCC).These findings are consistent with the result reported in litratures. 1,[8][9][10][11] However, a study realized by olufunso simisola aduayi et al is contrary to our results which shouts SCC constitute over 80% of all malignancies that arise in the nasomaxillary area. 7 CT scan is the most frequently used radiological investigation to evaluate nasomaxillary swelling lesions.…”

Section: Discussioncontrasting

confidence: 67%

Nasomaxillary swellings: our experience at tertiary care hospital

Rawat

Lall

Sachdeva

2021

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

Background: A wide spectrum of lesions may present as nasomaxillary swellings ranges from benign to malignant lesions including fungal sinusitis and fibro vascular lesions example: JNA (Juvenile nasopharyngeal angiofibroma) and Inverted papilloma. Many Pathologies ranging from benign to malignant tumors may mimic a simple Nasomaxillary mass. It is diagnostic challenge to determine pathology behind it. A detailed clinical evaluation with nasal endoscopy and relevant pre-operative investigations including radiological imaging and histopathological examination is essential to reach up to final diagnosis. The aim of the study was to do clinicopathological evaluation of patients presenting with nasomaxillary swelling and correlation of clinical, radiological and Histopathological findings.Methods: This was a prospective observational study on 50 nasomaxillary swelling patients who are presented in the Department of ENT and Head and Neck Surgery of N.S.C.B. MCH Jabalpur, a tertiary care Hospital, between March 2018 to August 2019. A detailed history taking and clinical examination with nasal endoscopy and relevant preoperative investigations including CECT Nose and PNS and histopathological examination was done in all patients.Results: 50 Nasomaxillary swelling patients were selected for this study. 30 patients were male and 20 were females. Ages of patients were varied from 12 years to 72 years. 23 patients (46%) were malignant and 27 (54%) were benign. Histopathological examination results shows benign lesions like JNA (6 cases), fungal sinusitis (6 cases), dermoid cyst (1 case), inverted papilloma (3 cases), sebaceous cyst (1 case), jaw lesions (10 cases), (odontogenic like radicular/ infected cyst, dentigerous cyst, cystic ameloblastoma and non-odontogenic like fibrous dysplasia) and malignant lesions like SCC (squamous cell carcinoma) (12 cases), spindle cell sarcoma (2 cases), undifferentiated carcinoma (3 cases), adenocarcinoma (3 cases), adenoid cystic carcinoma (1 case), Invasive pleomorphic sarcoma (1 case) and malignant melanoma (1 case). SCC was most common lesion f/b JNA and fungal sinusitis. Well differentiated SCC was most common histological type (10 out of 12 cases of SCC). Most common symptom was nasal obstruction (66% cases) f/b epistaxis (52% cases) but epitasis was most common symptom among malignant and JNA cases. In 6 cases (3 JNA, 1 inverted papilloma, 1 malignancy and 1 radicular cyst) radiological diagnosis were not correlated with histological findings.Conclusions: Most our cases were malignant nasomaxillary lesions followed by fungal sinusitis and JNA. Most patients presented in advanced stage of disease so rapidly evaluation including nasal endoscopy should be done. CECT scan is essential to determine tumors extent and bony lesions. All patients should undergo hisotopatholigical examination. The final diagnosis should be made on the basis of clinical, radiological and histopathological findings.

show abstract

Section: Discussioncontrasting

confidence: 67%

Nasomaxillary swellings: our experience at tertiary care hospital

Rawat

Lall

Sachdeva

2021

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…Although sensitive, S100 is not specific. More specific markers include HMB45, Melan-A or anti-tyrosinase, which stain about 75% of lesions [1][2][3][4][5]. The morphological and immunohistochemical picture was on the same lines in our case also.…”

Section: Discussionsupporting

confidence: 61%

“…Because most melanomas are asymptomatic in their early stages, the diagnosis is unfortunately often delayed until symptoms. Neck nodal metastases to cervical lymph nodes, occurs in 10-50% cases [5][6][7][8]. In the case being discussed here, the patient was a 57-year-old male who complained of nasal bleeding and nasal obstruction since 6-7 months.…”

Section: Discussionmentioning

confidence: 93%

Sinonasal Mucosal Melanoma- An Intriguing Case Report

Rawat¹

2022

Corpus J Case Rep

View full text Add to dashboard Cite

Introduction Primary Mucosal melanomas of the head and neck region are a rare kind of malignancy arising from the melanocytes. The primary melanomas of the paranasal sinuses are extremely unusual and associated with a poor prognosis due to delayed diagnosis. These lesions tend to metastasize and locally invade tissues more than any other malignant tumour of the head and neck region. Case report Here, we present a case of a fifty-seven-year-old male who presented with epistaxis and nasal obstruction. Imaging revealed a soft tissue mass lesion involving the maxillary sinus and nasal cavity with erosion of the floor of right orbit. Discussion The mainstay of treatment for these sinonasal mucosal melanomas is surgical resection followed by adjuvant radiotherapy or

show abstract

“…Regional lymphnode metastasis and distant metastasis to the bone, lungs and liver have also been reported in advanced cases. 2 Physiologic pigmentation, melanotic macule, smoker's melanosis, drug-induced melanosis, melanocytic naevus and pigmentation due to systemic causes like Addison's disease, Peutz-Jeghers syndrome, etc may be considered in the differential diagnosis. 3 Histologically atypical melanocytes, with hyperchromatism and nuclear pleomorphism in the junction of the epithelium and connective tissue together with immunohistochemical markers positive for S-100, HMB-45 are considered confirmatory for the diagnosis of MM.…”

Section: Descriptionmentioning

confidence: 99%