Malignant meningioma with extracranial metastases

Estanislau, Eduardo Simões; Carvalho, Gervásio Teles Cardoso de; Reis, Baltazar Leão; Barbosa, Warley de Freitas; Brandão, Rafael Augusto Castro Santiago; Sousa, Atos Alves de; Oliveira, João Batista de

doi:10.1590/s0004-282x2009000400036

Cited by 22 publications

(26 citation statements)

References 8 publications

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“…1 According to WHO criteria, the histologic grade of the tumor is the most important predictive factor for recurrence and metastasis. [2][3][4][5] However, metastatic meningioma may present in isolation without coexistent or previous local tumor recurrence, as seen in our patient. 3 However, these features are not essential for the occurrence of extracranial metastasis, and any histologically benign meningioma has the potential to metastasize.…”

Section: Discussionsupporting

confidence: 53%

“…3 The recurrence rate for benign tumors is 3% at 5 years and 21% at 25 years. 2 Other factors include high cellularity, mitotic rate, nuclear pleomorphism, presence of foci of necrosis, and invasion of adjacent structures. 1 According to WHO criteria, the histologic grade of the tumor is the most important predictive factor for recurrence and metastasis.…”

Section: Discussionmentioning

confidence: 99%

“…2 We describe a patient with delayed hepatic metastasis of a benign fibroblastic meningioma that was detected 31 years after surgical resection of the intracranial meningioma. Extracranial metastasis from benign meningiomas is exceedingly rare and is seen in less than 0.1% to 0.2% of cases.…”

Section: Introductionmentioning

confidence: 99%

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Delayed Hepatic Metastasis From a Benign Fibroblastic Meningioma Thirty-One Years After Surgical Resection of the Intracranial Tumor

Rampurwala

Pazooki

Schauer

2011

JCO

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

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Delayed Hepatic Metastasis From a Benign Fibroblastic Meningioma Thirty-One Years After Surgical Resection of the Intracranial Tumor

Rampurwala

Pazooki

Schauer

2011

JCO

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“…Extracranial metastases of meningiomas are rare and occur in less than 1 per 1000 cases [3, 4,5,6]. The most common site of metastasis is the lung, which counts for 61% of all meningioma metastases [7,8], followed by the liver, lymph nodes, and bones [9].…”

Section: Introductionmentioning

confidence: 99%

Intrakranijinės besimptomės meningiomos daugybinės metastazės į plaučius: klinikinis atvejis

Ušinskienė¹,

Letautienė²,

Šestelinska³

et al. 2016

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BackgroundThis case presents unexpected association between diseases and symptoms. We believe that it should compel clinicians to rethink the known behaviors of the benign tumors, in particular meningioma which can gain independent metastatic potential. This report aims to increase the awareness of clinicians toward patients with this unusual and clinically isolated pattern, because metastases can remain misdiagnosed for a long period of time. This case contributes to medical knowledge, diagnostic and prognostic approaches. This is also the first case of metastatic meningioma reported in Lithuania. Case presentationWe report a 66-year-old woman who presented with persistant productive cough, dyspnea, fever and weakness during physical activity. Chest radiographs revealed multiple small round shaped pulmonary nodules. Thoracoscopic resection and histopathology showed a benign meningioma. Magnetic resonance imaging scan of the brain demonstrated a small dural based mass in the left pontocerebellar angle connected with deep dilated cerebral venous network and superior petrosal sinus. Morphological findings of the session were consistent with a World Health Organization grade I fibrous meningioma. Klinikinė praktika 157Multiple pulmonary metastases from asymptomatic benign intracranial meningioma: case report ConclusionMeningiomas are usually non-invasive tumors and do not metastasize and hence, are perceived as benign tumors. Patients with this uncommon and clinically isolated pattern of metastases can remain misdiagnosed for a long period of time, due to unexpected behavior of this particular tumor. This case report denies most of the criteria of possible risk factors for the development of metastases from a meningioma what allows to consider it as tumor with unpredictable behavior. Key words: case report, meningioma, benign, asymptomatic, metastases. ĮvadasŠis klinikinis atvejis yra nenumatyto ligos pasireiškimo. Tikime, kad jis privers apgalvoti jau žinomą gerybinių navikų, tarp jų ir meningiomos, elgseną, kuri gali įgyti nepriklausomą metastazinį potencialą. Kadangi gerybinių navikų metastazės yra diagnozuojamos pavėluotai, šiuo pavyzdžiu siekiame plėsti klinicistų sąmoningumą ir budrumą nagrinėjant ligas, kurioms būdingos neįprastos klinikinės apraiškos. Tai pirmasis Lietuvoje aprašytas intrakranijinės meningiomos metastazavimo į plaučius atvejis. Atvejo pristatymasAprašome klinikinį atvejį 66 metų moters, kurią vargino nuolatinis produktyvus kosulys, dusulys, karščiavimas ir silpnumas, atsirandantis fizinio krūvio metu. Atliktos krūtinės ląstos rentgenogramos parodė daugybinius, mažus, apvalios formos mazgus plaučiuose. Po atliktos torakoskopinės plaučių audinių rezekcijos histopatologinio tyrimo metodu konstatuota meningioma. Atliktas galvos smegenų magnetinio rezonanso tyrimas, kurio išvada -kairiajame tilto ir smegenėlių kampe su dangalais susijęs, kontrastinę medžiagą gerai kaupiantis, smulkus navikas, išsiplėtusios giliosios smegenų venos. Histologinė smegenų darinio išvada remiantis Pasaulio sveikatos o...

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“…Extracranial metastases of meningiomas are rare and occur in less than 1 per 1000 cases [3,4,5,6]. The most common site of metastasis is the lung, which counts for 61% of all meningioma metastases [7,8], followed by the liver, lymph nodes, and bones [9].…”

Section: Introductionmentioning

confidence: 99%

Daugybinės plaučių metastazės iš besimptomės gerybinės intrakranijinės meningiomos: klinikinis atvejis

Ušinskienė¹,

Šestelinska²,

Neverauskiene³

et al. 2016

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InroductionThis case presents unexpected association between disease and symptoms. We believe that it should compel clinicians to rethink the known behaviors of the benign tumors, in particular meningioma which can gain independent metastatic potential. This report aims to increase the awareness of clinicians toward patients with this unusual and clinically isolated pattern, because metastases can remain misdiagnosed for a long period of time. This case contributes to medical knowledge, diagnostic and prognostic approaches. This is also the first case of metastatic meningioma reported in Lithuania. Case reportWe report a 66-year-old woman who presented with persistent productive cough, dyspnea, fever and weakness during physical activity. Chest radiographs revealed multiple small round shaped pulmonary nodules. Thoracoscopic resection and histopathology showed a benign meningioma. Magnetic resonance imaging (MRI) scan of the brain demonstrated a small dural-based mass in the left pontocerebellar angle connected with deep dilated cerebral venous network and superior petrosal sinus. Morphological findings of this tumor were consistent with a World Health Organization (WHO) grade I fibrous meningioma. 109Multiple pulmonary metastases from asymptomatic benign intracranial meningioma: a case report ConclusionMeningiomas are usually non-invasive tumors and do not metastasize and hence, are perceived as benign tumors. Patients with this uncommon and clinically isolated pattern of metastases can remain misdiagnosed for a long period of time, due to unexpected behavior of this particular tumor. This case report denies most of the criteria of possible risk factors for the development of metastases from a meningioma what allows to consider it as tumor with unpredictable behavior. Key words: meningioma, benign, asymptomatic, metastases Įvadas Šis klinikinis atvejis atspindi nenumatytą ligos pasireiškimą. Tikime, kad jis privers apgalvoti jau žinomą gerybinių navikų, tarp jų ir meningiomos, elgseną, kuri gali įgyti nepriklausomą metastazinį potencialą. Kadangi gerybinių navikų metastazės yra diagnozuojamos pavėluotai, šiuo pavyzdžiu siekiame plėsti klinicistų sąmoningumą ir budrumą nagrinėjant ligas, kurioms būdingos neįprastos klinikinės apraiškos. Tai pirmasis Lietuvoje aprašytas intrakranijinės meningiomos metastazavimo į plaučius atvejis. Klinikinis atvejisAprašome 66 metų moters atvejį. Ji skundėsi nuolatiniu produktyviu kosuliu, dusuliu, karščiavimu ir silpnumu, atsirandančiu fizinio krūvio metu. Krūtinės ląstos rentgenogramos parodė daugybinius, mažus, apvalios formos mazgus plaučiuose. Po atliktos torakoskopinės plaučių rezekcijos histopatologinio tyrimo būdu konstatuota meningioma. Atliktas galvos smegenų magnetinio rezonanso tyrimas, kurio išvada -kairiajame tilto ir smegenėlių kampe su dangalais susijęs, kontrastinę medžiagą gerai kaupiantis, smulkus navikas, išsiplėtusios giliosios smegenų venos. Histologiškai smegenų darinys, remiantis Pasaulio sveikatos organizacijos klasifikacija, yra I laipsnio fibrozinė meni...

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Malignant meningioma with extracranial metastases

Cited by 22 publications

References 8 publications

Delayed Hepatic Metastasis From a Benign Fibroblastic Meningioma Thirty-One Years After Surgical Resection of the Intracranial Tumor

Delayed Hepatic Metastasis From a Benign Fibroblastic Meningioma Thirty-One Years After Surgical Resection of the Intracranial Tumor

Intrakranijinės besimptomės meningiomos daugybinės metastazės į plaučius: klinikinis atvejis

Daugybinės plaučių metastazės iš besimptomės gerybinės intrakranijinės meningiomos: klinikinis atvejis

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