1987
DOI: 10.2214/ajr.149.5.1059
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Malignant nerve-sheath neoplasms in neurofibromatosis: distinction from benign tumors by using imaging techniques

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Cited by 131 publications
(51 citation statements)
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“…MRI may be helpful in diagnosis of malignant change. 67 Ga citrate scintigraphy has been advised in-patients of neurofibromatosis with suspected malignant change [11] as only malignant cells have been found to take up 67 Ga.…”
Section: Discussionmentioning
confidence: 99%
“…MRI may be helpful in diagnosis of malignant change. 67 Ga citrate scintigraphy has been advised in-patients of neurofibromatosis with suspected malignant change [11] as only malignant cells have been found to take up 67 Ga.…”
Section: Discussionmentioning
confidence: 99%
“…Certain peripheral nerve masses do present unique characteristics. 18,26 The majority of tumors show enhancement following administration of contrast agents like Gd (Figs. 3 and 4).…”
Section: Magnetic Resonance Imagingmentioning
confidence: 99%
“…28 Despite many advances in technology and technique, MR imaging is still limited in its ability to identify aspects of tumor pathology such as tumor grade or malignancy accurately. 5,18,26,27 Picking up small changes in size or volume of mass lesions is also difficult on MR imaging. In addition, the appearance and intensity of images obtained with MR imaging may change from one patient to another and between multiple runs on the same patient.…”
Section: Magnetic Resonance Imagingmentioning
confidence: 99%
“…4,34,37,38 Inhomogeneity in MPNSTs seems to reflect coexisting areas of hypo-and hypercellularity rather than regressive changes like necrosis or hemorrhage. 33,44 Initial efforts to discern neurofibromas and plexiform neurofibromas from MPNSTs have been successful recently with the use of FDG-PET. 6,15,16,43 However, false-positive results have been detected as well.…”
Section: Ambiguous Findingsmentioning
confidence: 99%