Malignant Oral Tumors in Iran

Sargeran, Katayoun; Murtomaa, Heikki; Safavi, Seyed Mohammadreza; Vehkalahti, Miira M.; Teronen, Olli

doi:10.1097/01.scs.0000246728.23483.ce

Cited by 39 publications

(25 citation statements)

References 16 publications

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“…The finding of this study that OSCC constitutes 41% of all oral malignancies was in sharp contrast to most previous studies which showed that OSCC accounts for 70-95% of all oral malignancies (3,11-13). However, our finding was consistent with that of Ajayi et al (8) who reported that OSCC accounts for 44% of all oral malignancies.…”

Section: Discussioncontrasting

confidence: 99%

A review of 640 Oral squamous cell carcinoma cases in Nigeria

2017

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BackgroundOral squamous cell carcinoma (OSCC) is the most prevalent malignant neoplasm in the oral cavity and accounts for 70% to 90% of all oral malignant neoplasms. The aim of this study was to examine the demographic distribution of OSCC in five Tertiary Health centres in Nigeria.Material and MethodsAll cases diagnosed as OSCC during the period from 1970 -2014 were retrieved from the records of five teaching hospitals in Nigeria. Hematoxylin and eosin stained histological slides of all cases that had a diagnosis of OSCC were reviewed for confirmation and inclusion. Data from all the centers was collated at the University College Hospital, Ibadan by 2 researchers. The data was entered into and analyzed with the SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL). Simple descriptive and comparative analyses were done, with the test of statistical significance set at p ≤ 0.05.ResultsA total of 640 cases of OSCC were seen out of 1560 oral malignant neoplasms representing 41% of all the oral malignancies seen. The mean age of occurence of OSCC was 55.5 (±17.0) years and a peak age incidence in the sixth and seventh decades of life. OSCC occurred more in males (60.9%) than females (39.1%) with a male: female ratio of 1.6:1. The well differentiated OSCC with 309 (48.3%) cases, was the most common grade, while the moderately differentiated and poorly differentiated OSCC accounted for 232 (36.2%) and 92 (14.4%) cases respectively.ConclusionsThis study showed that OSCC is more common in males, most commonly seen in the 60-69 age group and the commonest site of occurrence was the mandibular mucosa. The well differentiated OSCC was the most common histology sub-type. Key words:Oral squamous cell carcinoma, tongue, palate, mandible.

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Section: Discussioncontrasting

confidence: 99%

A review of 640 Oral squamous cell carcinoma cases in Nigeria

2017

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“…Last but not least, illiteracy, poverty and chronic debilitating diseases are prevalent in Yemen. Among populations with somewhat similar circumstances like Nigerians (22), Thais (6), Brazilians (15) and Iranians (23), high proportion of advanced oral cancer has been reported (100%, 73%, 65% and 50% respectively). On the other side, high proportion of oral cancer cases in the developed world are diagnosed at early stages (12,24).…”

Section: Discussionmentioning

confidence: 99%

Oral squamous cell carcinoma among Yemenis: Onset in young age and presentation at advanced stage

Halboub¹,

Al-Mohaya²,

Abdulhuq³

et al. 2012

J Clin Exp Dent

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Objectives: Oral cancer represents a health burden worldwide. Up to 90% of oral cancer cases are squamous cell carcinomas (SCC). The data on oral SCC in Yemen are lacking. The objective of this study therefore was to describe and analyze the demographic, clinical and histological characteristics of Yemeni patients with oral SCC. Study Design: In this cross-sectional study, two sets of retrospective data for Yemeni cancer patients were obtained officially by two different registries. Patients with oral SCC were included. Their ages were dichotomized using 40 and 45 years alternately as individual cut-points for young and old patients. The patients` demographic, clinical and histological characteristics were statistically analyzed. Results: There were 457 Yemenis with oral SCC; 253 patients (55.4%) were men. The overall mean age was 58.15±14.11 years. The tongue was the most affected oral sub-site accounting for 53% of the reported cases. The well and moderately differentiated oral SCC accounted for 55.5% and 25.6% of the total cases respectively. Noteworthy, 62 patients (14%) were affected by the age of ?40; this increased to 105 patients (23%) aged ?45 years. Additionally, a high proportion of oral SCC patients (62%, 283) were diagnosed at advanced tumor stages (regional extension or metastasized). The distributions of histological grades and tumor stages in young and old patients were significantly different (P=0.006 and 0.026 respectively). Conclusion: The relative frequency of oral SCC among Yemeni young people is high. Unfortunately, most of oral SCC patients in Yemen were diagnosed at advanced stage. Key words:Oral squamous cell carcinoma, Yemen, young patients, advanced stage.

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“…Due to limited access to diagnostic and treatment services in low-income communities and to the high cost of services, people present with advanced stage lip and oral cavity cancer at the time of diagnosis. All the aforementioned are among the important reasons for the low 5-year survival of patients as well as the higher mortality rates in developing countries (Funk et al, 2002;Global Burden of Disease Cancer, 2015;Patel et al, 2012;Sargeran et al, 2008). McDonald et al reported in their study that there was lower survival of head and neck cancers, including oral cavity cancer, in people of low socioeconomic statuses (McDonald et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

The incidence and mortality of lip and oral cavity cancer and its relationship to the 2012 Human Development Index of Asia

Tiyuri

Mohammadian-Hafshejani

Iziy

et al. 2017

Biomed. Res. Ther.

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Introduction: Lip and oral cavity cancer is one of the most prevalent cancers in Asia and considered to be a major public health problem due to the low survival rate. Because of the importance of access to information about this cancer (including incidence, mortality rate and relation to socioeconomic indicators), this study aims at investigating the incidence and mortality of lip and oral cavity cancer and its relationship with the Human Development Index (HDI) of Asia (from 2012). Method: This study was an ecological study in Asia for assessment of the correlation between age-specific incidence rate (ASIR) and age-specific mortality rate (ASMR) with the HDI and its components which include: life expectancy at birth, mean years of schooling and gross national income (GNI) per capita. Data on the standardized incidence ratio (SIR) and the standardized mortality ratio (SMR) for every Asian country for the year 2012 were obtained from the global cancer project and data on the HDI and its components were extracted from the World bank site.

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Malignant Oral Tumors in Iran

Cited by 39 publications

References 16 publications

A review of 640 Oral squamous cell carcinoma cases in Nigeria

A review of 640 Oral squamous cell carcinoma cases in Nigeria

Oral squamous cell carcinoma among Yemenis: Onset in young age and presentation at advanced stage

The incidence and mortality of lip and oral cavity cancer and its relationship to the 2012 Human Development Index of Asia

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