Malignant proliferating trichilemmal tumor in abdominal wall: Report of a rare case at an uncommon site with literature review

Azizi, Mahdokht; Ramezani, Mazaher

doi:10.1002/ccr3.5259

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…The occurrence of PPT is infrequent, and its biological activity is characterized by unpredictability. Histologically, there is a frequent confusion between pilomatricoma (PTT) and malignant proliferating trichilemmal tumor (MPTT), as well as metastatic or invasive squamous cell carcinoma (SCC) [2]. This particular case exhibits a unique instance of multiple proliferating trichilemmal tumors accompanied by a positive family history, hence posing a diagnostic challenge.…”

Section: Prefacementioning

confidence: 99%

Multiple Proliferating Trichilemmal Tumor with Positive Family History: A Case Report and Review of the Literature

Chen,

Ren,

Zhong

et al. 2023

cmf

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Objective: Proliferating trichilemmal tumor is uncommon tumors that develop from the hair follicle's outer root sheath. They frequently correspond to the transition of a simple trichilemmal cyst, and they typically occur on the scalp of elderly women. However, multiple proliferating trichilemmal tumor are more rare and difficult to diagnose. Therefore, the diagnosis and treatment of this disease were discussed based on the relevant literature and the clinical data of multiple proliferating trichilemmal tumor in our hospital. Methods: The clinical data of a 74 year old female patient with multiple proliferating trichilemmal tumor and positive family history admitted to department of dermatology were retrospectively analyzed, combined with relevant literature review and discussion. Results: After surgical radical treatment, it is suggested to be multiple proliferating trichilemmal tumor based on the pathological result and immunohistochemical results. Conclusion: Proliferating trichilemmal tumors a rare but morphologically distinctive tumor. The diagnosis is mainly based on pathological results. Based on the histopathologic findings of tumor, this case was diagnosed as proliferating trichilemmal tumor. Surgery is the first choice for treatment. The patient's condition was successfully treated with total excision. Regular postoperative review is required. Proliferating trichilemmal tumor need to be diagnosed and treated using a multidisciplinary strategy. Close clinical follow-up is the most efficient method of early metastasis and recurrence detection.

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Section: Prefacementioning

confidence: 99%

Multiple Proliferating Trichilemmal Tumor with Positive Family History: A Case Report and Review of the Literature

Chen,

Ren,

Zhong

et al. 2023

cmf

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“…In 1983, Saida et al [ 5 ] documented the initial case of malignant PTT (MPTT)[ 6 ]. Distorted mitosis, cytological diversity, peripheral infiltration, and aneuploidy have been observed across various cases[ 7 ]. PTT itself is a rarity, and the occurrence of MPTT accompanied by lymph node metastasis is exceedingly infrequent[ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Malignant proliferative ependymoma of the neck with lymph node metastasis: A case report

Wang,

Wen,

Zhou

et al. 2023

World J Clin Cases

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β cells are the main cells responsible for the hypoglycemic function of pancreatic islets, and the insulin secreted by these cells is the only hormone that lowers blood glucose levels in the human body. β cells are regulated by various factors, among which neurotransmitters make an important contribution. This paper discusses the effects of neurotransmitters secreted by various sympathetic and parasympathetic nerves on β cells and summarizes the mechanisms by which various neurotransmitters regulate insulin secretion. Many neurotransmitters do not have a single source and are not only released from nerve terminals but also synthesized by β cells themselves, allowing them to synergistically regulate insulin secretion. Almost all of these neurotransmitters depend on the presence of glucose to function, and their actions are mostly related to the Ca2+ and cAMP concentrations. Although neurotransmitters have been extensively studied, many of their mechanisms remain unclear and require further exploration by researchers.

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Malignant proliferating trichilemmal tumor in abdominal wall: Report of a rare case at an uncommon site with literature review

Abstract: The proliferating trichilemmal tumor (PTT) is a very rare cutaneous neoplasm that rarely is malignant. PTTs mainly occur in the scalp of elderly women. Only 10% occur in places other than scalp. We present a 62‐year‐old male patient with malignant PTT in his abdominal wall.

Cited by 2 publications

References 19 publications

Multiple Proliferating Trichilemmal Tumor with Positive Family History: A Case Report and Review of the Literature

Multiple Proliferating Trichilemmal Tumor with Positive Family History: A Case Report and Review of the Literature

Malignant proliferative ependymoma of the neck with lymph node metastasis: A case report

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