Malignant Sacrococcygeal Teratoma with Yolk Sac Differentiation in a Child—A Case Presentation

Abstract

Sacrococcygeal teratoma (SCT) is a common congenital neoplasm, contains derivatives of more than one of the three embryonic germ cell layers. However, malignant Sacrococcygeal Yolk Sac tumor (YST) is an extremely rare extra-gonadal germ cell tumor. This case describes a two and half years old female child presenting with history of swelling at sacrococcygeal region for nine months. Case was evaluated clinically. Patient's serum alpha fetoprotein (AFP) level was elevated abnormally. FNAC of the swelling was done which shows suspicious cell for immature teratoma. Swelling excised and histopathological examination was carried out, the report of which shows malignant sacrococcygeal teratoma with yolk sac tumor.

A Rare Case of Extragonadal Mixed Germ Cell Tumor of the Sacrococcygeal Region with Mature Thymic Tissue in the Teratoma Component

“…Teratoma is the most common benign histology of sacrococcygeal GCTs accounting for 32%–66%,[ 3 ] and the most common malignant histology is the yolk sac tumor, which is frequently admixed with teratoma,[ 2 ] as was present in our case.…”

Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature

“…Regarding the differentiation between immature SCT and malignant forms, according to Altman's classification, most of the immature forms, according to the studies, were classified as types I/II [23], whereas the malignant forms were of type III/IV and predominantly feminine fetuses [69,70].…”