Malignant schwannoma following treatment for Hodgkin's disease

Fisher, P.M.; Bridges, Leslie; Cartwright, S.C.; Stone, Jonathan

doi:10.1016/s0936-6555(94)80063-4

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Imaging of the RTC is only indicated if the clinical assessment, including history and physical examination, is not consistent with what is expected or if the patient does not respond to initial treatment measures and surgical intervention is contemplated. Although rare, HL survivors are at risk for radiation‐induced malignancies such as malignant peripheral nerve sheath tumors, and these should be included in the differential diagnosis of shoulder pain and dysfunction (Figure 7) [50,51].…”

Section: Common Clinical Syndromesmentioning

confidence: 99%

Radiation Fibrosis Syndrome: Neuromuscular and Musculoskeletal Complications in Cancer Survivors

Stubblefield

2011

PM&R

179

130

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Radiation-induced toxicity is a major cause of long-term disability after cancer treatment. Radiation fibrosis describes the insidious pathologic fibrotic tissue sclerosis that can occur in response to radiation exposure. Radiation fibrosis syndrome describes the myriad clinical manifestations of progressive fibrotic tissue sclerosis resulting from radiation treatment. Radiation-induced damage can include "myelo-radiculo-plexo-neuro-myopathy," causing muscle weakness and dysfunction and contributing to neuromuscular injury. Similarly, radiation damage to neuromuscular structures contributes to radiation-induced trismus and cervical dystonia in head and neck cancer survivors. This narrative review discusses the pathophysiology, anatomy, evaluation, and treatment of neuromuscular, musculoskeletal, and functional disorders that can result as late effects of radiation treatment. Rehabilitation medicine physicians with extensive training in neuromuscular and musculoskeletal medicine as well as in the principles of functional restoration are uniquely positioned to help lead efforts to improve the quality of life for cancer survivors with radiation fibrosis syndrome.

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Section: Common Clinical Syndromesmentioning

confidence: 99%

Radiation Fibrosis Syndrome: Neuromuscular and Musculoskeletal Complications in Cancer Survivors

Stubblefield

2011

PM&R

179

130

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“…Schwannomas as secondary tumors after treatment of Hodgkin's lymphoma, radiotherapy in particular, have been well documented [1][2][3]. The present case of synchronous Hodgkin's disease and schwannomas prior to any therapy is highly unusual.…”

mentioning

confidence: 95%

Synchronous Hodgkin’s lymphoma and schwannomas mimicking refractory Hodgkin’s lymphoma

Leeksma

Haas²,

Hofman

et al. 2015

Ann Hematol

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“…Review of the literature reveals only 5 reported cases of radiationinduced malignant schwannomas in patients treated for Hodgkin disease, all found in the European literature. 3,4 To our knowledge there is no other case report of a secondary benign schwannoma.…”

mentioning

confidence: 96%