Malignant Schwannoma in patients with von Recklinghausen disease: report of two cases

Freitas, Vinicius Antunes; Saliba, Michel Cyrino; Moraes, Eduardo Cesar Dolabela de; Teixeira, Gabriela Amélia Nassif de Morais; Oliveira, João Batista de

doi:10.1016/s1808-8694(15)30851-x

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“…Шванномы (нейрилеммомы) представляют собой опухоли, состоящие из хорошо дифференцированных шванновских клеток, происходящих из глиальных клеток оболочек периферических нервов [1]. Большинство шванном являются доброкачественными, а злокачественные, которые обычно связаны с болезнью фон Реклингхаузена, встречаются редко [2,3]. Поскольку для шванном малого таза нет специфических клинических или рентгенологических признаков и они напоминают ряд заболеваний органов малого таза, может быть легко поставлен ошибочный диагноз [4,5].…”

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Clinical case of surgical treatment of a malignant tumor from the sheaths of peripheral nerves of retroperitoneal localization

Atakhanova,

Tursunova,

Yahyaeva

et al. 2024

Onkol. koloproktol.

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Clinical case. The article presents a clinical case of malignant retroperitoneal schwannoma, which was a diagnostic finding. The clinical picture of the disease was dominated by pain in the lower abdomen and lower back, frequent urination. After a diagnostic examination and preliminary preparation, the patient was operated on in a hospital at the oncogynecology department of the Tashkent City branch of the Republican Specialized Scientific and practical Medical Center of Oncology and Radiology with a preliminary diagnosis of an ovarian tumor. Interrooperatively, a tumor of the retroperitoneal space with lesions of the obturator nerve was revealed. Subsequently, immunohistochemical analysis clarified the histological type of the tumor, which turned out to be a malignant schwannoma of the retroperitoneal space.Conclusion. These data may help in the management of patients with this pathology and improve the diagnosis of patients with small pelvic tumors.

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