Malignant skin lesions in Oshogbo, Nigeria

Oseni, Ganiyu Oyediran; Olaitan, Peter B; Komolafe, Akinwumi Oluwole; Olaofe, Olaejirinde Olaniyi; Akinyemi, Hezekiah Adebola Morakinyo; Suleiman, Oreoluwa Adeola

doi:10.11604/pamj.2015.20.253.2441

Cited by 12 publications

(18 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They are histological varieties with different clinical and prognostic expressions. The high prevalence of squamous cell carcinomas and melanoma in blacks unlike basal cell carcinomas among whites was reported by several studies [4] [5] [6]. In our context, skin cancers are of late diagnosis.…”

Section: Introductionsupporting

confidence: 54%

Outcomes of Surgical Treatment of Skin Cancer at Surgical Oncology Unit of Donka, Conakry University Hospital

Traoré¹,

Lamah²

2017

JCT

View full text Add to dashboard Cite

Aim: The main aim of this study was to evaluate outcomes after surgical treatment of skin cancer. Methods: This retrospective cohort study concerned 46 patients who presented 43 skin cancers lesions surgically treated at surgical oncology unit, Conakry University Hospital. There were 29 (61.7%) squamous cell carcinoma, 12 (25.5%) melanoma, 4 (8.5%) sarcomas and 1 (2.1%) porocarcinoma. Surgical indications and prognosis factors were analyzed. Results: Surgical treatment included simple excision in 2 cases (3.8%), wide excision in 38 cases (71.7%) and amputation/disarticulation in 13 cases (24.5%). Inguinal lymph node dissection was performed in 16 patients (34.3%). Postoperative complications were wound suppuration (5 cases), lower limb lymphedema (4 cases), seroma (2 cases) and skin flap necrosis (1 case). Surgical margins were free in 28 (60.9%) patients, infiltrated in 3 patients (6.5%) and unspecified in 15 patients (32.6%). The median follow-up after surgery was 29 months. During the follow-up, 13 patients (28.3%) had a relapse. The relapse was influenced by surgical margins (p = 0.012) and iterative resection (p = 0.04). Overall survival was 65.2%. Factors related to survival in univariate analysis were: iterative resection (p = 0.008), fungated tumor (p = 0.037), the status of surgical margins (p = 0.002) and the occurrence of relapse (p = 0.0000). In multivariate analysis, the status of surgical margins was the only independent prognostic factor. Conclusion: The prognosis after surgical treatment of cutaneous cancers depends on the resection margins.

show abstract

Section: Introductionsupporting

confidence: 54%

Outcomes of Surgical Treatment of Skin Cancer at Surgical Oncology Unit of Donka, Conakry University Hospital

Traoré¹,

Lamah²

2017

JCT

View full text Add to dashboard Cite

show abstract

“…This higher prevalence may be due to the inclusion of biopsied cases only and therefore suggests the prevalence of skin cancer among skin biopsy specimen while excluding a large population of cases whose lesions were not biopsied. The most frequently observed primary skin cancer was squamous cell carcinoma, and it occurs at a frequency of 33.3% and at a mean age of 39.3 years This is however in contrast with the review of biopsy specimen at other Centre where melanoma was found to be most frequent (6,7).…”

Section: Discussionmentioning

confidence: 80%

“…The prevalence of skin cancers have previously been reported in some centres in Ni-geria. A prevalence of 5.5% was reported in Osogbo, whereas a prevalence of 27% was reported in Benin (6,7). While the incidence of skin cancers may still be higher in the Caucasians, an alteration in the ratio of the incidence as well as in the prevalence may require verification.…”

Section: Introductionmentioning

confidence: 97%

The Evolving Pattern Of Primary Skin Cancers in Ile-Ife, Nigeria

Oripelaye

Oladele

Olanrewaju

et al. 2018

Serbian Journal of Dermatology and Venereology

Self Cite

View full text Add to dashboard Cite

Background. The increasing solar intensity and HIV epidemic have progressively eroded the protective effects of melanin among black race. This study was aimed at evaluating the pattern of primary skin cancers in Ile-Ife, Nigeria. Methods. This retrospective study, which was conducted at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, included the patients diagnosed with primary skin cancers between January 2008 and December 2017. The data were analyzed using SPSS version20. Results. The frequency of primary skin cancers was 1.0%. Females (58.3%) outnumbered the males (41.7%), the ratio being 1.4:1. The spectrum of primary skin cancers documented by this study are squamous cell carcinoma (33.3%), malignant melanoma (25%), Kaposi sarcoma (15.3%), basal cell carcinoma (9.7%), and cutaneous lymphoma (6.9%). Conclusion. Melanin remains a major protective factor for skin cancers among negroids. Albinism and high burden of HIV were identified risk groups for skin cancers. The eradication of HIV and enhanced sun protection will reduce the prevalence of skin cancers.

show abstract

“…Noneless the 'barefoot' notion and of traumas as part of the disease history allowed in their cohort retrieved PPMM in farmers with a tendency to walk barefoot in their farm [9,10]. To note that 81,7% of the cases we observed, the lesion localized in the pressure point of the extremities, sole and heel, which explain the pressure exercised at that level associated with a reduced melanin level in that region.…”

Section: Discussionmentioning

confidence: 96%