Malignant transformation of ovarian mature cystic teratoma in a postmenopausal woman presented as acute abdomen

Abstract

Malignant transformation of mature cystic teratomas is uncommon but present in clinical practice. Especially in postmenopausal women, the clinical manifestation of a mature teratoma with undiagnosed malignant transformation as acute abdomen is extremely rare. In these cases, total hysterectomy with bilateral salpingo-oophorectomy is the treatment choice since the chance of malignancy is high. The prognosis is good if the cyst is not ruptured, is completely excised and the cancer does not extend beyond the capsule. In any other case, the prognosis is unfavorable since recurrence is common and the tumor is chemoresistant.

Rare case of squamous cell carcinoma arising in a recurrent ovarian mature cystic teratoma of a young woman

“…Although the application of FIGO staging to SCCs in the case of MCTs does not clearly relate to the graduated outcome of the disease, patients with FIGO stages II to IV had a lower probability of long-term survival than patients with stage I disease. [ 18 , 23 ] Age, tumor size, clinical stage, histologic differentiation, capsular invasion, and the presence of vascular invasion can provide valuable information for the prediction of the survival of patients with SCCs arising from MCTs. [ 5 , 10 , 18 ] The early diagnosis of the malignant transformation before invasion or metastasis is important for treatment.…”

Medical management of cesarean scar pregnancy at advanced age: case report and literature review

“…There is no agreement in the literature on treatment due to rarity of the condition. Expectant treatment, D&C, local or systemic MTX, local potassium chloride application, embolization of uterine artery, laparoscopic excision, and hysterectomy were all suggested for different clinic presentations of the disease [7,8]. Early and accurate diagnosis is essential for the utilization of various treatment options and preventing serious complications [7,8].…”

“…Expectant treatment, D&C, local or systemic MTX, local potassium chloride application, embolization of uterine artery, laparoscopic excision, and hysterectomy were all suggested for different clinic presentations of the disease [7,8]. Early and accurate diagnosis is essential for the utilization of various treatment options and preventing serious complications [7,8]. In this paper, the authors discuss a six to seven week old cesarean scar ectopic pregnancy that was successfully treated with MTX thanks to early diagnosis and include a brief literature review.…”