Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor

Ghailane, Soufiane; Fauquier, Sandra; Lepreux, Sébastien; Huec, Jean-Charles Le

doi:10.1007/s00586-017-5277-2

Cited by 4 publications

(2 citation statements)

References 9 publications

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“…We compiled data on reported cases of MTT in the recent 6 years (2018–2023, Table 1). 1,6–38 There were totally 37 cases with a mean age of 39.4 years (range 8 months old–75 years old), including 24 male and 13 female patients. Eleven cases originated in the abdomen (30%), 10 cases in the head and neck (27%), 8 cases in the thoracic cavity (21%), 6 cases in the limbs (16%), 1 case in the spine (3%), and 1 case in the buttocks (3%).…”

Section: Results Of Literature Reviewmentioning

confidence: 99%

Malignant triton tumor of uterus: A case report and literature review

Jiang,

Liu,

et al. 2023

J of Clinical Ultrasound

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Malignant triton tumor (MTT) is a highly aggressive malignant neoplasm, classified as a variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. There are few reports that MTT occurred in urogenital system. In the present study, we report the first MTT occurring in the uterus. A 57‐year‐old woman came to the emergency department due to persistent vaginal bleeding for 2 months. The gynecological palpation found that a club‐shaped excrescence existed in the vagina about 7 cm × 3 cm × 3 cm. The mass located in the lower segment of the uterus and the cervix was confirmed by gynecological vaginal ultrasound and magnetic resonance imaging, which was preliminarily diagnosed as cervical carcinoma. After neoplasm punch biopsy, the pathological diagnosis was malignant triton tumor. The patient finally lost follow‐up. This is the first report about MTT in the uterus and suggests that pathological biopsy combined with imaging examination is necessary for the diagnosis of rarely MTT.

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Section: Results Of Literature Reviewmentioning

confidence: 99%

Malignant triton tumor of uterus: A case report and literature review

Jiang,

Liu,

et al. 2023

J of Clinical Ultrasound

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“…Despite the availability of master-class diagnostic tools and consensus guidelines in surgical oncology for most of abdominal tumors, no standard management plan for MTT is available in literature [ [8] , [9] , [10] ]. Nevertheless, some recommendations have been proposed [ 11 ]. Furthermore, the prognosis of MTT is poor as reported by a 5-year survival rate of only 5 to 15% [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Malignant triton tumor of the rectum – A case report and review of the literature

Herzberg

Corradini

Seydewitz

et al. 2020

International Journal of Surgery Case Reports

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Expert’s comment concerning Grand Rounds case entitled "Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor" by S. Ghailane et al. (Eur Spine J; 2017: DOI 10.1007/s00586-017-5277-2)

Choi

2018

Eur Spine J

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The authors report a case of malignant triton tumor of the spine, presenting at the thoracolumbar of a 70 year old gentleman, with back pain and left leg pain of two years duration. Unfortunately, 3 months after complete marginal resection, the patient developed local recurrence and seeding to the cauda equina, and died 10 months after diagnosis. Malignant triton tumor is a rare variant of malignant peripheral nerve sheath tumor that has rhabdomyoblastic differentiation [1]. The tumor originates from neural crest cells, and is a high grade sarcomatous lesion. Median age at presentation is 29 years, with male to female ratio 1.5:1. Overall survival at 18 months is around 45%, but adverse factors include incomplete resection, spinal involvement, size greater than 2cm, or association with neurofibromatosis. Accepted treatment is complete excision and post-operative radiotherapy, and sometimes chemotherapy. However, as in this case, resection of extensive spinal tumors is rarely complete.

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Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor

Abstract: Based on the Grand Round case and relevant literature, we present a case of a highly aggressive and fast-growing tumor with a very high local and distant recurrence. There is no consensus treatment plan available and patients usually die shortly after diagnosis.

Cited by 4 publications

References 9 publications

Malignant triton tumor of uterus: A case report and literature review

Malignant triton tumor of uterus: A case report and literature review

Malignant triton tumor of the rectum – A case report and review of the literature

Expert’s comment concerning Grand Rounds case entitled "Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor" by S. Ghailane et al. (Eur Spine J; 2017: DOI 10.1007/s00586-017-5277-2)

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