Malignant Tumours of the Ear

Lederman, M.

doi:10.1017/s0022215100063465

Cited by 126 publications

(45 citation statements)

References 9 publications

(3 reference statements)

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“…1,4 Modern skull base resection techniques are a critical component in treatment and are responsible for improving survival rates from less than 20% to greater than 50%. 1,4,7,8,10,12,13 In this series, overall local disease control was maintained at 74%.…”

Section: Neurosurg Focus / Volume 12 / May 2002mentioning

confidence: 57%

Lateral skull base malignancies

McGrew¹,

Jackson²,

Redtfeldt³

2002

FOC

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Object Historically poor outcomes have been characteristic in patients with lateral skull base malignancies. As advances in skull base surgical techniques have been made, complete resection has increasingly been achieved. This has resulted in improved survival rates and local tumor control. Methods The authors performed a retrospective review of 95 patients treated for lateral skull base malignancies. The mean age of the patients was 49.4 years. There were 44 females and 51 males. The mean follow-up period was 50 months. Resection was performed in all patients, and postoperative radiotherapy was undertaken in 54% of the cases. Local disease control was maintained in 73% of the patients. Tumor involvement of the facial nerve and intracranial tumor extension did not jeopardize the rate of local control. Conclusions Despite the fact that technical advances in skull base surgery have resulted in a higher incidence of complete tumor resection and improved survival rates, a respect for the poor prognosis historically associated with lateral skull base malignancies should be maintained and treatment should be appropriately aggressive.

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Section: Neurosurg Focus / Volume 12 / May 2002mentioning

confidence: 57%

Lateral skull base malignancies

McGrew¹,

Jackson²,

Redtfeldt³

2002

FOC

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“…SCC constitutes 82% of the tumors involving the auditory canal, middle ear, and mastoid [10] while adenoid cystic carcinoma [ACC] is seen only in 6-10% of all cases [11]. Chronic superlative otitis media and previous irradiation are thought of as etiological factors [12].…”

Section: Discussionmentioning

confidence: 99%

Hearing Loss Revealing a Squamous Cell Carcinoma of External Auditory Canal in a Post-Irradiated Patient for Nasopharyngeal Carcinoma

Chafiki¹

2017

MOJBM

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Background: Primary Carcinoma of external auditory canal (EAC) is a rare disease accounting for less than 2% of head and neck cancers and has an annual incidence of around 1 per million populations. EAC carcinoma in postirradiated nasopharyngeal carcinoma (NPC) patients occurs with an incidence of approximately 0.15%. It arises from the external ear and spreads to the temporal bone and surrounding sites. Although its rarity, it is a life threatening disease with practically a poor constant prognosis. Primary EAC carcinoma can occur with no specific symptoms. Aggressive surgery with postoperative radiation remains the usual treatment until now. We report a rare case of a squamous cell carcinoma (SCC) of EAC revealed by a progressive hearing loss as first presentation of the disease in a post-irradiated woman for NPC. Results:A 47-year-old female with a past medical history of nasopharyngeal carcinoma treated with chemo radiation therapy, presented for repeated leftsided purulent ear discharge and progressive hearing loss. Otoscopic examination revealed a tissue mass filling the left EAC. CT scan revealed a soft tissue density process filling the EAC, encroaching upon the tympanic cavity and coming into contact with the handle of the malleus neither with no acicular lyses nor EAC walls erosion. The biopsy of the mass was consistent with EAC SCC. The patient under went lateral temporal bone resection with homolateral superficial parotidectomy and selective neck dissection and completed by an adjuvant external radiation therapy [RT]. Conclusion:Post-irradiation EAC SCC has similar symptoms and invades similar regions as its primary counterpart. This entity is usually discovered in the early stage in post-irradiated EAC SCC patients comparing to the primary EAC SCC. Aggressive surgical treatment is strongly recommended, but adjuvant radiotherapy for early stage EAC SCC should be provided cautiously to prevent further radiation induced complications.

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“…Carcinomas (squamous cell carcinoma and adenocarcinoma) are the most common malignant tumors arising in the ear (75-90%) [1][2][3]. Other malignant tumors reported to develop in the middle ear are melanoma, rhabdomyosarcoma, chondrosarcoma, lymphoma and metastatic malignancies (breast, lung and renal) [4].…”

Section: Discussionmentioning

confidence: 99%

Lymphoma in the Ear

Merkus¹,

Copper²,

Oers

et al. 2000

ORL

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Background: Malignant tumors of the ear are rare. The most common malignant tumors are squamous cell carcinomas and adenocarcinomas. Lymphoma in the ear is rare. Methods: We report 2 cases of a primary presentation of a lymphoma of the ear. The literature since 1947 is reviewed. Results: An 83-year-old woman with an anaplastic large cell lymphoma of the skin of the external auditory meatus and a 75-year-old man with a B-cell non-Hodgkin’s lymphoma of the mastoid process are presented. The literature review shows that only 16 cases of lymphomas of the ear have been reported so far. Conclusions: In a case of therapy-resistant otitis and/or peripheral facial paralysis malignancy should be excluded by computer tomography of the mastoid. For histopathological diagnosis unfixed specimens are preferable. Uniform treatment of lymphomas of the ear has not been established.

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Malignant Tumours of the Ear

Cited by 126 publications

References 9 publications

Lateral skull base malignancies

Lateral skull base malignancies

Hearing Loss Revealing a Squamous Cell Carcinoma of External Auditory Canal in a Post-Irradiated Patient for Nasopharyngeal Carcinoma

Lymphoma in the Ear

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