Malnutrition in tuberculosis: value of fat-free mass and creatinine-height index

Mohamed-Hussein, Aliaeë A. R.; Salama, Suzan; Khalil, Medhat A.; Eid, Samir

doi:10.4103/1687-8426.176790

Cited by 3 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most patients with active tuberculosis are in a catabolic state and present weight loss associated with vitamin and mineral deficiency at the time of diagnosis (Mohamed-Hussein et al, 2016). Hyponatremia is defined as a serum sodium level below 135 mmol/L and is a common problem among hospitalized patients, reported in both acute and chronic diseases (Korzelius et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil

Biadola¹,

Correa²,

Aguiar³

et al. 2020

RSD

View full text Add to dashboard Cite

Objective: Evaluate the severity of tuberculosis and its association with laboratory tests before antituberculosis treatment. Methodology: Patients with pulmonary tuberculosis were evaluated for severity using data available in medical records (Clinical; Excretion of mycobacteria; and Diagnostic imaging) and associated with biochemical and hematological parameters requested at the time of diagnosis and before antituberculosis treatment. Results: The evaluation of the severity showed a predominance of smear AFB (+), fever associated with other symptoms and infiltrative tuberculosis. Only a positive correlation between mycobacteria excretion and imaging diagnosis (rho=0.47; p=0.023) was observed. The patients presented hyponatremia (9/21), hypomagnesemia (6/13), and hypercalcemia (1/13), unrelated to the severity. The presence of fever influenced the number of non-segmented neutrophils (p=0.0142) and the total leukocyte count correlated with the increase in total neutrophils (rho=0.9631; p<0.0001). Conclusion: Different severity characteristics of tuberculosis, although they reflect the degree of commitment of the patient, are not always correlated; the evaluation of electrolytes could contribute to clinical behavior; and non-segmented neutrophils are associated with a worse clinical prognosis in patients with tuberculosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil

Biadola¹,

Correa²,

Aguiar³

et al. 2020

RSD

View full text Add to dashboard Cite

show abstract

“…It concludes that TB patients have reduced body weight significantly with loss of lean body weight, fat weight and low creatinine and serum albumin index. 23 Several studies have found that active TB patients have less BMI compared to well-nourished people. 24 In a study from Indonesia, the average BMI of the patients with active TB was one fifth lower than in controls.…”

Section: Nutritional Status and Tuberculosismentioning

confidence: 99%

Nutritional Burden in Tuberculosis and Inter-sectoral Nutritional Management for Tuberculosis Patients in Malaysia

Mokti¹,

Isa²,

Manaf³

et al. 2020

Turkiye Klinikleri J Med Sci

View full text Add to dashboard Cite

ABS TRACT Undernutrition and tuberculosis (TB) are a vital issue in most developing countries of the world. Both of these medical problems tend to have interacted with each other and bidirectional. The undernutrition creates a more significant problem in patients with active TB rather than among healthy individuals. Despite that, there is no protocol available on nutritional support in Malaysia to tackle on this issue. The objective of this review is to explore the nutrition burden of TB disease and the management available in Malaysia. The treatment for TB lasts for six months and above. Hence, it causes a financial burden not only for the healthcare provider but for the patient and the family members. If treatment is not successful and extends to a few months, it will increase the cost of the treatment. Malnutrition in TB patients will cause a problem in the outcome of TB treatment. It includes worsening of the disease, delayed sputum conversion, and increased risk of mortality. Other problems include malabsorption of Rifampicin, drug-induced hepatotoxicity, increased rate of relapse, and persistent of positive cultures in MDR-TB. Benefits of nutritional support for tuberculosis patients include improved body weight, increase in adherence/compliance to the tuberculosis treatment and increase in the success of the treatment. Implementation of nutritional support protocol by the government and Non-profit organization (NGO) will be beneficial and improve the quality of life of tuberculosis patients.ÖZET Beslenme yetersizliği ve tüberküloz (TB) dünyanın gelişmekte olan birçok ülkesinde hayati bir konudur. Bu tıbbi sorunların her ikisi de birbirleriyle etkileşime girme ve çift yönlü olma eğilimindedir. Beslenme yetersizliği, sağlıklı bireylerden ziyade aktif TB'li hastalarda daha önemli bir problem yaratır. Buna rağmen, Malezya'da bu konuda mücadele edecek beslenme desteği konusunda protokol bulunmamaktadır. Bu derlemenin amacı TB hastalığının beslenme yükünü ve Malezya'da bulunan yönetimi araştırmaktır. TB tedavisi altı ay ve daha uzun sürer. Dolayısıyla, sadece sağlık hizmeti sağlayıcısı için değil, hasta ve aile üyeleri için finansal bir yüke neden olmaktadır. Eğer tedavi başarılı olmaz ve birkaç aya kadar uzarsa, tedavinin maliyetini yükseltir. TB hastalarındaki yetersiz beslenme, TB tedavisinin sonucunda bir soruna neden olacaktır. Hastalığın kötüleşmesini, balgam dönüşümünü geciktirmeyi ve ölüm riskini arttırmayı içerir. Diğer problemler arasında Rifampisin salgılanması, ilaca bağlı hepatotoksisite, artmış nüks oranı ve MDR-TB'de pozitif kültürlerin kalıcılığı bulunur. Tüberküloz hastaları için beslenme desteğinin faydaları arasında vücut ağırlığının iyileştirilmesi, tüberküloz tedavisine uyumun artması ve tedavinin başarısının artması yer alır. Devlet ve sivil toplum kuruluşları (STK) tarafından beslenme destek protokolünün uygulanması yararlı olacak ve tüberküloz hastalarının yaşam kalitesini artıracaktır.Anah tar Ke li me ler: Kötü beslenme; beslenme durumu; tüberküloz; Malezya ndernutrition and tuberculosi...

show abstract

Adverse outcome pathway for aminoglycoside ototoxicity in drug-resistant tuberculosis treatment

et al. 2019

View full text Add to dashboard Cite

Individuals treated for multidrug-resistant tuberculosis (MDR-TB) with aminoglycosides (AGs) in resource-limited settings often experience permanent hearing loss. However, AG ototoxicity has never been conceptually integrated or causally linked to MDR-TB patients' pre-treatment health condition. We sought develop a framework that examines the relationships between pre-treatment conditions and AG-induced hearing loss among MDR-TB-infected individuals in sub-Saharan Africa.

show abstract

Malnutrition in tuberculosis: value of fat-free mass and creatinine-height index

Cited by 3 publications

References 14 publications

Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil

Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil

Nutritional Burden in Tuberculosis and Inter-sectoral Nutritional Management for Tuberculosis Patients in Malaysia

Adverse outcome pathway for aminoglycoside ototoxicity in drug-resistant tuberculosis treatment

Contact Info

Product

Resources

About