Malnutrition risk is associated with hypoglycemia among general population admitted to internal medicine units. Results from the MENU study

Abstract

Our data suggest increased malnutrition risk as measured by the NRS2002 almost doubled the risk for hypoglycemia during the hospitalization.

Association of albumin and cholesterol levels with incidence of hypoglycaemia in people admitted to general internal medicine units

“…However, our data suggest that, even when controlling for age, inflammatory markers, renal status and acute infections, albumin remains significantly associated with hypoglycaemia. Furthermore, hypocholesterolaemia was also found to be associated with hypoglycaemia risk, also increasing the likelihood of malnutrition as a contributing factor, for the occurrence of hypoglycaemia .…”

“…Weight was not measured in this population, and as a result, we cannot establish a nutrition status for participants. However, a previous study indicated that weight loss and/or reduced food intake preceding the admission is a key factor associated with increased rates of hypoglycaemia .…”

“…Severely malnourished people have been shown to have hypoglycaemia and diabetes, but this was observed mostly in developing countries . Recently, elevated malnutrition risk measured at hospital admission using the Nutrition Risk Screen 2002 was found to predict hypoglycaemia among hospitalized individuals regardless of diabetes status . The study also showed that albumin upon admission was lower among people with hypoglycaemia.…”

“…E-mail: heartman@matav.net.il ª 2018 Diabetes UK developing countries [12]. Recently, elevated malnutrition risk measured at hospital admission using the Nutrition Risk Screen 2002 was found to predict hypoglycaemia among hospitalized individuals regardless of diabetes status [13].…”

Prediction of Hypoglycemia During Admission of Non-Critically Ill Patients: Results from the MENU Study

“…The pathophysiology of hypoglycemia is not fully understood, and it is suspected that the cause differs according to DM status: among DM patients, hypoglycemia is associated with strict glucose control [16], and considered to be caused by over-treatment, while in patients without DM, hypoglycemia is commonly thought to be associated with severity of illnesses [15]. We recently showed that high malnutrition risk is associated with hypoglycemia, regardless of DM status [17]. We also found that albumin and cholesterol, two blood markers that are associated with the nutritional status of patients [18], are also predictive of hypoglycemia incidence among patients admitted to internal medicine units [19].…”