Mammalian and Plant Carbonic Anhydrases: Structure, Function, Mechanism and Control

Pocker, Y.

doi:10.1007/978-94-009-0663-1_8

Enzymatic and Model Carboxylation and Reduction Reactions for Carbon Dioxide Utilization 1990

DOI: 10.1007/978-94-009-0663-1_8

|View full text |Cite

Mammalian and Plant Carbonic Anhydrases: Structure, Function, Mechanism and Control

Y. Pocker

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2000

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

References 106 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Water in enzyme reactions: biophysical aspects of hydration-dehydration processes

Pocker

2000

CMLS, Cell. Mol. Life Sci.

Self Cite

View full text Add to dashboard Cite

Water has been recognized as one of the major structuring factors in biological macromolecules. Indeed, water clusters influence many aspects of biological function, and the water-protein interaction has long been recognized as a major determinant of chain folding, conformational stability, internal dynamics, binding specificity and catalysis. I discuss here several themes arising from recent progress in understanding structural aspects of 'direct' and 'indirect' ligands in terms of enzyme-substrate interactions, and the role of water bridges in enzyme catalysis. The review also attempts to illuminate issues relating to efficiency, through solvent interactions associated with enzymic specificity, and versatility. Over the years, carbonic anhydrase (CA; carbonate hydrolyase, EC 4.2.1.1) has played a significant role in the continuing delineation of principles underlying the role of water in enzyme reactions. As a result of its pronounced catalytic power and robust constitution CA was transformed into a veritable 'laboratory' in which active site mechanisms were rigorously tested and explored.

show abstract

Water in enzyme reactions: biophysical aspects of hydration-dehydration processes

Pocker

2000

CMLS, Cell. Mol. Life Sci.

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Mammalian and Plant Carbonic Anhydrases: Structure, Function, Mechanism and Control

Cited by 1 publication

References 106 publications

Water in enzyme reactions: biophysical aspects of hydration-dehydration processes

Water in enzyme reactions: biophysical aspects of hydration-dehydration processes

Contact Info

Product

Resources

About