Mammary hibernoma

Gardner-Thorpe, Damian; Hirschowitz, Lynn; Maddox, P R

doi:10.1053/ejso.1999.0913

Cited by 18 publications

(14 citation statements)

References 2 publications

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“…Although these tumors can arise in various sites, mammary hibernomas remain extraordinarily uncommon, with fewer than 10 cases reported thus far in the English literature. [1][2][3][4][5] This review discusses the clinical presentation, radiologic and histopathologic features, ancillary studies, pathogenesis, differential diagnoses, and treatment of and prognosis for this rare entity.…”

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confidence: 99%

Mammary Hibernoma: A Rare Entity

Riley

Karamchandani²

2014

Archives of Pathology &Amp; Laboratory Medicine

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Hibernoma arising in the breast is rare and may present as an asymptomatic mass or may be detected by screening mammography. Four histologic types have been identified: typical, myxoid variant, spindle cell variant, and the lipoma-like variant. The most common “typical variant” is composed of pale to eosinophilic multivacuolated cells with interspersed univacuolar cells. Hibernomas are universally benign and are not known to recur or have an aggressive behavior, even in incompletely excised lesions. Hence, their clinical importance lies in distinguishing them from other benign and malignant breast neoplasms as well as inflammatory conditions that come into the histologic or radiologic differential. This review discusses the clinical features, radiologic and histopathologic characteristics, ancillary studies, suggested pathogenesis, differential diagnosis, and treatment of and prognosis for these uncommon lesions.

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confidence: 99%

Mammary Hibernoma: A Rare Entity

Riley

Karamchandani²

2014

Archives of Pathology &Amp; Laboratory Medicine

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“…So far, 6 cases have been reported as mammary hibernoma. [3][4][5][6][7] In the largest series of hibernomas to date, 2 of 170 cases were located in the breast. 4 Second entity is adenohibernoma, which harbors hibernoma containing glands.…”

Section: Discussionmentioning

confidence: 99%

Adenohibernoma

2011

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Adenohibernoma of the breast is a very rare tumor composed of brown fat tissue and intermingled glandular tissue. There are only 2 case reports in literature. This study reports the third case of adenohibernoma of the breast, which is not accompanied by breast cancer differing from the previous cases. And, to the best of the authors' knowledge, this is also the first case of adenohibernoma of the breast that has demonstrated adipophilin expression immunohistochemically.

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“…On breast ultrasound, the hibernoma is echogenic (Fig. 1c) (6). Uniform echogenicity on breast ultrasound is suggestive of a fatty lesion, and the differential diagnosis includes lipoma, fibrolipoma, fibroadenolipoma, normal interlobular stromal fibrous tissue, pure capillary hemangioma, and early fat necrosis (7).…”

Section: Discussionmentioning

confidence: 99%

Mammary Hibernoma

et al. 2006

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We report the case of a 39-year-old asymptomatic woman who presented for screening mammography. Mammography revealed a round, partially circumscribed, partially indistinct, noncalcified 4.5 cm mass in upper outer right breast. This vaguely palpable mass appeared as a well-circumscribed, oval, hyperechoic, parallel, septated mass on sonography. Ultrasound-guided core biopsy led to the diagnosis of hibernoma. Few cases of hibernomas have been reported in the English literature, and their occurrence in the breast is particularly rare [Eur J Surg Oncol 26 (2000) 430; Am J Surg Pathol 25 (2001) 809]. To our knowledge, this is the first case of mammary hibernoma in which the ultrasonographic and mammographic features of this unusual entity are demonstrated.

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Mammary hibernoma

Abstract: Hibernomas are rare benign tumours of brown fat. We report the first account in the English literature of a mammary hibernoma, presenting in the post-lactational period.

Cited by 18 publications

References 2 publications

Mammary Hibernoma: A Rare Entity

Mammary Hibernoma: A Rare Entity

Adenohibernoma

Mammary Hibernoma

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