Management and outcome of neuroendocrine tumours of the appendix—a two centre UK experience

Systematic review and meta‐analysis of appendiceal carcinoid tumors in children

“…reported an incidence of 1.14 per million per year in children . Most are incidental findings following removal of an appendix specimen for acute appendicitis . The dilemma has been what care to provide following incidental histological identification of an appendiceal carcinoid.…”

“…Several pediatric studies have questioned the use of these guidelines in children and the benefit of more extensive procedures like RHC following the incidental histological diagnosis of an appendiceal carcinoid …”

“…The management of appendiceal carcinoids in children has remained controversial as most of the algorithms available were developed from the adult experience . Moreover, these tumors also seem to behave differently in children prompting several authors to question if more extensive procedures other than simple appendicectomy are necessary . The aim of the study was to review the literature regarding past and current practices in managing incidental appendiceal carcinoid tumors and the need for more procedures after appendicectomy.…”

ENETS Consensus Guidelines for Neuroendocrine Neoplasms of the Appendix (Excluding Goblet Cell Carcinomas)

“…The reason for the even better outcome in the pediatric population is currently not understood [5,63]. …”

Neuroendokrine Neoplasien des gastroenteropankreatischen Systems

“…In diesen seltenen Fällen verschlechtert sich die Prognose drastisch (10-Jahres-Überlebensrate von 30 %) [42,43]. Bei einer Tumorgröße von 1-2 cm sollten präoperativ eine Endosonographie und funktionelle Bildgebung erfolgen, um eine eventuelle Invasion der Muscularis propria beurteilen zu kön-nen.…”