The chapter examines the issue of changing the regional regulatory practice of the Russian Federation in the regulation of the general education assessment system. The monitoring results confirm the lack of a consistent approach in the federal subjects to regulate activities on the general education quality assessment. However, there is a positive trend—the number of federal subjects in which an integrated approach is used to regulate the general education quality assessment is increasing. An integrated approach is most accurately reflected by the provisions on the regional system for assessing the general education quality that is developed and approved in federal subjects. These regulatory legal documents are aimed (1) to obtain up-to-date, objective, and reliable information about the education quality in the federal subjects of Russia and (2) to achieve a balance in the activities of bodies and structures in the subjects to consolidate efforts to improve the quality of education.