Management of advanced parotid cancer. A systematic review

Immune regulatory cells and IL17-producing lymphocytes in patients with benign and malignant salivary gland tumors

“…The incidence may substantially vary with race/ethnicity and geographic areas [1][2][3]. These tumors * Corresponding author.…”

Carcinoma of the parotid gland: developing prognostic indices

“…In the present study, patients with present or previous head and neck squamous cell carcinomas were excluded from the analysis. Adenoid cystic carcinomas can have a prolonged and unpredictable natural history 15 . In the authors' series, adenoid cystic carcinomas, probably due to their small number, did not show a worse prognostic than other types.…”

What is new in the management of salivary gland cancers?

“…Risk factors for disease recurrence after surgical resection have been reported by multiple authors and include advanced local disease extent (T), incomplete surgical resection, bone invasion, named nerve involvement, positive surgical margins, nodal involvement, and worse histopathologic grading [4,[8][9][10]. Although never tested in a prospective randomized clinical trial, the use of postoperative radiation therapy in those patients with a high risk of local or regional recurrence appears to improve disease control [8][9][10][11][12]. As such, radiation therapy has been adopted as a standard of care in patients at high risk for recurrence after surgical resection.…”