2006
DOI: 10.2147/tcrm.2006.2.3.281
|View full text |Cite
|
Sign up to set email alerts
|

Management of age-related osteoporosis and prevention of associated fractures

Abstract: Osteoporosis and related fractures are a significant concern for the global community. As the population continues to age, morbidity and mortality from fractures due to low bone mineral density (BMD) will likely continue to increase. Efforts should be made to screen those at risk for osteoporosis, identify and address various risk factors for falls and associated fractures, ensure adequate calcium and vitamin D intake, and institute pharmacological therapy to increase BMD when indicated. Agents which increase … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

1
14
0

Year Published

2009
2009
2019
2019

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 23 publications
(15 citation statements)
references
References 115 publications
1
14
0
Order By: Relevance
“…Interestingly, both males and females were more likely to report an increased number of risk factors as age increased. In agreement with our results, numerous studies have been demonstrated that osteoporosis is an age-related disorder that affects the bones as people get older [20,21]. Moreover, the risk for osteoporosis is greater for females after the age of 50 years old (usually occurs between the ages of 45 and 55) according to the International Osteoporosis Foundation due to being post menopause, as a consequence broken bones, because of hormonal changes during menopause that could lead to rapid loss bone mass [22,23].…”
Section: Discussionsupporting
confidence: 93%
“…Interestingly, both males and females were more likely to report an increased number of risk factors as age increased. In agreement with our results, numerous studies have been demonstrated that osteoporosis is an age-related disorder that affects the bones as people get older [20,21]. Moreover, the risk for osteoporosis is greater for females after the age of 50 years old (usually occurs between the ages of 45 and 55) according to the International Osteoporosis Foundation due to being post menopause, as a consequence broken bones, because of hormonal changes during menopause that could lead to rapid loss bone mass [22,23].…”
Section: Discussionsupporting
confidence: 93%
“…As the population continues to age, morbidity and mortality from fractures due to low bone mineral density will likely continue to increase. 19) Efforts need to be made to screen those at risk of osteoporosis and identify the potential pathological mechanisms for age-related osteoporosis. Our study is the first to report the gene expression of RAS components in bone tissue by the polymerase chain reaction, in accordance with the results which showed the protein expression of ACE, rennin and angiotensin II receptors in the tibia 6) and femur 20) of mice.…”
Section: Discussionmentioning
confidence: 99%
“…Fractures, whether attributable to PMO or to CTIBL, can significantly decrease mobility, functional autonomy, and quality of life [19]; and greatly increase disease-management costs [10]. Moreover, fractures are also associated with reduced survival (especially in the first 6 months post-fracture) [10].…”
Section: Reviewmentioning
confidence: 99%