Management of airway complications after lung transplantation: is there an ideal stent?

Martinod, Emmanuel; Dutau, Hervé; Guibert, Nicolas

doi:10.21037/jtd-22-858

Cited by 7 publications

(4 citation statements)

References 26 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, this is the largest posttransplant series with this type of airway stent. In total 5 (8.8%) adverse events occurred, all of which could be remedied with a single bron- Though it meets almost all 20 standards, the major positive feature of BDS is also its main limiting factor, the stents dissolve. This study shows a mean life span of 112 days until fully dissolving, which means for chronic treatment it is a labor intensive and expensive treatment.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Lung transplant airway complications treated with biodegradable airway stents: The Dutch multi‐center experience

van Pel,

Gan,

Daniels

et al. 2024

Clinical Transplantation

View full text Add to dashboard Cite

IntroductionTreatment of post lung‐transplant airway complications is challenging, and treatment with conventional airway stents is associated with adverse events. More recently, biodegradable airway stents (BDS) have been introduced and may be used to reduce these adverse events. In this study we explore the feasibility of treatment with BDS post lung transplant.MethodsAll patients treated with BDS in The Netherlands were included in this retrospective multicenter study. Feasibility, life span of the stent, occurrence of adverse events, and evolution of lung function were evaluated.ResultsTwelve patients (six malacia and six stenosis) received a total of 57 BDS, ranging from 1 to 10 BDS per patient. Six patients had been pretreated with conventional airway stents. Median stent life span was 112 days (range 66–202). No adverse events occurred during stent placement. In 5 out of 57 stent placements, a single additional bronchoscopy was necessary because of mucus accumulation (n = 4) or excessive granulation tissue (n = 1). All stent naïve patients became airway stent independent after treatment; all patients pretreated with conventional airway stents were still airway stent dependent at the end of follow up.ConclusionTreatment with BDS is safe and feasible. Adverse events were mild and easily treatable. All patients with initial treatment with BDS were airway stent independent at the end of follow up with a median treatment of 4 BDS.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Though it meets almost all 20 standards, the major positive feature of BDS is also its main limiting factor, the stents dissolve. This study shows a mean life span of 112 days until fully dissolving, which means for chronic treatment it is a labor intensive and expensive treatment.…”

Section: Discussionmentioning

confidence: 99%

Lung transplant airway complications treated with biodegradable airway stents: The Dutch multi‐center experience

van Pel,

Gan,

Daniels

et al. 2024

Clinical Transplantation

View full text Add to dashboard Cite

show abstract

“…(A) (B) (A) (B) In addition to malignant airway obstructions and CAO, other airway disorders such as tracheoesophageal fistulae, bronchopleural fistulae, anastomotic dehiscence after lung transplantation or resection, and tracheobronchomalacia have all been managed with airway stenting at various times [13][14][15]. Post-tracheotomy or post-intubation airway stenosis, as well as post-infectious airway stenosis (particularly due to tuberculosis) have also been reported to be indications for airway stenting in specific clinical scenarios [7,[16][17][18][19][20][21]. Particularly in benign airway disease, however, a multidisciplinary team approach to patient care, with early involvement of surgical specialists, is necessary for optimal disease management.…”

Section: Indications For Stent Placementmentioning

confidence: 99%

“…The ideal airway stent should have several characteristics [16,33]. First, it should be easy to deploy but also easy to remove when no longer needed.…”

Section: General Principles In Stent Selectionmentioning

confidence: 99%

Airway Stents in Interventional Pulmonology

Bashour,

Lazarus

2024

JoR

View full text Add to dashboard Cite

Airway stents, first developed in the 1980s, have become fundamental in managing a multitude of airway pathologies and complications within the field of interventional pulmonology. The primary function of an airway stent is to re-establish airway patency and integrity when obstruction, stenosis, anastomotic dehiscence, or fistulae develop as a result of various malignant or benign conditions. Nevertheless, airway stents are foreign bodies that can result in complications. In this review article, we will discuss airway stents and their ongoing role in the management of several malignant and benign diseases. We will describe indications for airway stenting and review the elements that must be taken into consideration for optimal patient and stent selection. Given the prevalence of data regarding therapeutic bronchoscopy and airway stenting in malignant airway obstruction, much of the discussion in this review will focus on stent placement for that indication. We will also review the data as it pertains to safety, efficacy, and complications after stent placement, and conclude with a discussion of the future applications and research avenues related to airway stents.

show abstract

Airway Complications Related to Lung Transplantation

Kafi,

Taylor,

Cheng

2024

Curr Pulmonol Rep

View full text Add to dashboard Cite

Purpose of Review This review describes the pathophysiology and risk factors associated with airway complications post lung transplant. We discuss the different types of airway complications (AC) and their management based on recent literature reviews and institutional experience. Recent Findings AC are now less frequent due to improvements in procurement, surgical techniques, and post-operative management of lung transplant. Risk factors for AC are well described and involve both donor and recipient factors. The management of airway complications is not universally agreed upon, and data regarding the efficacy of different modalities is limited. Summary Airway management requires a multidisciplinary approach between interventional pulmonary, lung transplant, and occasionally surgical teams. With small or limited airway defects, we advocate for conservative medical management. For more extensive airway complications, advanced bronchoscopic techniques may be utilized with good outcomes. Research is needed to validate the efficacy of customized silica stents for airway complications.

show abstract

Management of airway complications after lung transplantation: is there an ideal stent?

Cited by 7 publications

References 26 publications

Lung transplant airway complications treated with biodegradable airway stents: The Dutch multi‐center experience

Lung transplant airway complications treated with biodegradable airway stents: The Dutch multi‐center experience

Airway Stents in Interventional Pulmonology

Airway Complications Related to Lung Transplantation

Contact Info

Product

Resources

About