The Emergency Department of St Mary’s Hospital Paddington, has been involved in an ongoing programme of research into alcohol misuse since 1988. It has developed its own screening tool the Paddington Alcohol Test (PAT) and was one of the first to employ a resident alcohol health worker (AHW). This article will review the history of alcohol related research in this large inner London teaching hospital and illustrate the continuing development of alcohol identification and brief advice in the Emergency Department