Management of anaphylaxis in the dental practice:  an update

Jevon, Phil; Shamsi, Shaam

doi:10.1038/s41415-020-2454-1

Cited by 14 publications

(7 citation statements)

References 34 publications

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“…They ranked second in the list of causative agents among total SRsAs, pediatric SRsAs, and fatal SRsAs. LAs are typical triggers of anaphylaxis in dentistry practice [ 32 ], though the risk of true IgE-mediated allergy was shown to be lower than 1% [ 33 , 34 , 35 , 36 , 37 ]. Amide local anesthetics are less involved in hypersensitivity reactions compared with ether local anesthetics, and among the amides, lidocaine is known to be the most associated with severe allergic reactions.…”

Section: Discussionmentioning

confidence: 99%

Drug-Induced Anaphylaxis: National Database Analysis

Butranova,

Zyryanov,

Gorbacheva

et al. 2024

Pharmaceuticals

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(1) Background: National health system databases represent an important source of information about the epidemiology of adverse drug reactions including drug-induced allergy and anaphylaxis. Analysis of such databases may enhance the knowledge of healthcare professionals regarding the problem of drug-induced anaphylaxis. (2) Methods: A retrospective descriptive analysis was carried out of spontaneous reports (SRs) with data on drug-induced anaphylaxis (SRsAs) extracted from the Russian National Pharmacovigilance database (analyzed period 2 April 2019–21 June 2023). The percentage of SRsAs among SRs of drug-induced allergy (SRsDIAs) was calculated, as well as of pediatric, elderly, and fatal SrsAs. Drugs involved in anaphylaxis were assessed among total SRsAs, pediatric, and elderly SRsAs, and among fatal SRsAs. Demographic parameters of patients were assessed. (3) Results: SRsAs were reported in 8.3% of SRsDIAs (2304/27,727), the mean age of patients was 48.2 ± 15.8 years, and females accounted for 53.2% of cases. The main causative groups of drugs were antibacterials (ABs) for systemic use (44.6%), local anesthetics (20.0%), and cyclooxygenase (COX) inhibitors (10.1%). Fatal SRsAs were reported in 9.5% (218/2304) of cases, the mean age of patients was 48.0 ± 16.7 years, and females accounted for 56.4% of cases. Pediatric SRsAs accounted for 3.9% of pediatric SRsDIAs and 5.8% of all SRsAs, with a mean age of 11.8 ± 4.5 years, and females acccounted for 51.9% of cases. Elderly SRsAs accounted for 2% of elderly SRsDIAs and 2.8% of all SRsAs, and the mean age was 73.0 ± 5.3 years, and females accounted for 43.5% of cases. ABs caused 40% of SRsAs in the elderly, 42.9% in children, and 50% of fatal SRsAs. (4) Conclusions: Our study revealed a relatively high proportion of anaphylaxis among SRs of drug-induced allergy. ABs were the most prevalent causative agents, especially in fatal SRsAs.

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Section: Discussionmentioning

confidence: 99%

Drug-Induced Anaphylaxis: National Database Analysis

Butranova,

Zyryanov,

Gorbacheva

et al. 2024

Pharmaceuticals

View full text Add to dashboard Cite

show abstract

“…They were ranked second in the list of causative agents among total SRsAs, pediatric SRsAs, and among fatal SRsAs. LAs are typically considered to be anaphylaxis triggers prevalent in dentistry practice [32], though the risk of true IgEmediated allergy was shown to be lower than 1% [33 -37]. Amide local anesthetics are less involved in hypersensitivity reactions compared with ethers, and among amides lidocaine is known to be the most associated with severe allergic reactions.…”

Section: Discussionmentioning

confidence: 99%

Drug-induced Anaphylaxis: National Database Analysis

Butranova,

Zyryanov,

Gorbacheva

et al. 2023

Preprint

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(1) Background: National health system databases represent one of the most obvious sources of information about epidemiology of adverse drug reactions including drug-induced allergy and anaphylaxis. (2) Methods: Retrospective analysis of data from national database of pharmacovigilance in the Russian Federation (analyzed period 02.04.2019 - 21.06.2023) was performed. The prevalence of anaphylactic reactions (ARs) was determined, the structure of drugs involved was estimated together with patients’ characteristics. (3) Results: ARs were reported in 8.3% of drug-induced allergic reactions (2304/27,727), mean age of patients was 48.2 ± 15.8 years, 53.2% were females. Main causative groups of drugs were antibiotics, ABs (44.62%), local anesthetics, (19.97%), and cyclooxygenase (COX)-inhibitors (10.07%). Fatal ARs was reported in 9.5% (218/2304), mean age 48.0 ± 16.7 years, 56.2% females. Pediatric population accounted for 5.8% (133/2304), mean age 11.8± 4.5 years, 51.9% females. Elderly population accounted for 2.8% (65/2304), mean age 73.0±5.3 years, 43.5% (27/65) females. ABs were the leading causative groups of ARs in the elderly (40%), children (42.86%), and among fatal cases (50%). (4) Conclusions: ARs accounted for 8.3% of all drug-induced allergic reactions, and ABs were the most common causative agents. Females predominated in all groups except elderly patients.

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“…The common symptoms of latex allergy include skin reactions such as itching, redness, rash, or hives, itchy nose, throat, or eyes, nausea, abdominal cramps, and difficulty breathing. While most reactions occur within minutes of exposure, some skin reactions may not develop for 24-48 hours afterward [ 17 ]. Anaphylaxis, which could be a life-threatening condition, can occur and can cause a drop in blood pressure.…”

Section: Discussionmentioning

confidence: 99%

Rubber Dam Isolation for Bonding Ceramic Veneers: A Five-Year Post-Insertion Clinical Report

Jurado¹,

Fischer²,

Sayed³

et al. 2021

Cureus

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It has been well-documented that uncontaminated ground enamel provides the most predictable substrate for the bonding of ceramic veneers, and thus conservative tooth preparation with complete isolation using a rubber dam is key to the long-term success of the restorations presented with five years of follow-up. Rubber dam isolation provides several advantages to the clinician, such as preventing contamination of the working field by saliva, blood, and sulcular fluids, and improving direct visibility. However, it may be a challenge to the younger clinician to properly isolate teeth prior to bonding ceramic veneer. The present case report demonstrated the sequence and some clinical tips for a case in which the rubber dam is placed from a second premolar to the opposite second premolar and held with clamps, the rubber dam is gently invaginated into the sulcus, and clamps are selected and placed on each tooth to create an ideal situation for the adhesion of the ceramic veneer. This step-by-step sequence may help the younger clinician in understanding how to gently manage soft tissue in order to properly provide complete isolation with rubber dam for future bonding of ceramic veneers. Following these methods, the clinician can achieve complete isolation, invaginate the rubber dam in the sulcus without causing tissues to bleed, and reduce the time needed for bonding procedures.

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Management of anaphylaxis in the dental practice: an update

Cited by 14 publications

References 34 publications

Drug-Induced Anaphylaxis: National Database Analysis

Drug-Induced Anaphylaxis: National Database Analysis

Drug-induced Anaphylaxis: National Database Analysis

Rubber Dam Isolation for Bonding Ceramic Veneers: A Five-Year Post-Insertion Clinical Report

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