Management of ascites and volume overload in patients with cirrhosis

Abstract

Volume overload and ascites, or the accumulation of fluid in the abdomen, is a debilitating manifestation of chronic liver disease and portal hypertension that is associated with reduced survival and quality of life. [1,2] In patients with compensated cirrhosis, ascites occur in 5%-10% per year, and its onset is a key indicator of hepatic decompensation and progression of liver disease. [3] The presence of volume overload and, specifically, ascites increases the risk of additional complications, including malnutrition, infection, electrolyte imbalance, and hepatorenal syndrome.