Management of cardiovascular comorbidities in chronic obstructive pulmonary disease patients

Abstract

Chronic respiratory diseases (CRDs) cause enormous burden to the society. In 2016, these diseases were responsible for 3.8 million deaths or 7% of all global deaths. Seventy-five percent of these deaths occurred in those aged 30-69 years, demonstrating that CRDs are not solely a problem for the elderly (1). Chronic obstructive pulmonary disease (COPD) is a major CRD characterized by high prevalence and mortality, and by a persistent and usually progressive airflow limitation associated with different risk factors, the main of which being tobacco smoking and air pollution. Based on multiple large-scale epidemiological studies, the global prevalence of

Risk of Coronary Heart Disease in People with Chronic Obstructive Pulmonary Disease: A Meta-Analysis

“…The combined analysis results of this study show that COPD patients have a higher risk of CHD, and COPD is a risk factor for CHD, which is consistent with the current research on the mechanism of CHD. Though the mechanisms by which COPD increases CHD risk are not clear, patients with COPD often display abnormally high concentrations of circulating systemic inflammatory could be the main reason, [3][4][5][6] and the lung hyperinflation also represent one of the most important problem related to the high thoracic pressure that could be generated. 14 However, public or health professionals and patients with COPD still generally have insufficient understanding of "COPD increases the risk of developing CHD," leading to poor prevention of coronary heart disease.…”

“…3,4 COPD increases the risk of CHD due to chronic systemic/local inflammation. 1,[3][4][5][6] And traditional cardiovascular risk factors such as smoking, hypertension, hyperlipidemia are highly prevalent in patients with COPD, they could contribute to COPD progression. 7 Epidemiological studies have also shown that the incidence of cardiovascular death in patients with COPD is high.…”

High-Density Lipoproteins: A Role in Inflammation in COPD

“…This seems important given the high prevalence of comorbid course of COPD and atherosclerotic cardiovascular disease. Indeed, coronary heart disease and peripheral artery disease are common in COPD patients [ 68 , 69 ]. Such comorbidity mutually worsens the course of both diseases.…”

How to achieve the UN Sustainable Development Goals in the field of noncommunicable diseases by 2030, according to research in 49 countries

“…Изменения образа жизни и особенно пагубная роль курения в развитии ХОБЛ стали неотъемлемой частью проводимого ВОЗ 18 ноября каждого года Всемирного дня Международные аСПеКТы по борьбе с ХОБЛ. Поскольку ХОБЛ и ИБС часто встречаются у одного больного, общность подходов к лечению этих заболеваний очевидна, в частности снижение легочной функции тесно связано с высоким риском развития сердечной недостаточности, а большая часть больных с умеренными по тяжести формами ХОБЛ умирает от ССЗ чаще, чем от легочной недостаточности [31]. В соответствии со сказанным, непрерывная борьба с курением, регулярный контроль за заболеванием и интегральный подход к лечению ХОБЛ являются залогом сохранения достигнутого и дальнейшего снижения смертности от ХОБЛ.…”