Management of Chronic Peripheral Neuropathy

Hughes, Richard

doi:10.1177/147827150003000410

Journal of the Royal College of Physicians of Edinburgh

2000

DOI: 10.1177/147827150003000410

|View full text |Cite

Management of Chronic Peripheral Neuropathy

Richard Hughes

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2003

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 63 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Hughes

2003

Drugs

View full text Add to dashboard Cite

This review briefly describes current concepts concerning the nosological status, pathogenesis and management of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). CIDP is an uncommon variable disorder of unknown but probably autoimmune aetiology. The commonest form of CIDP causes more or less symmetrical progressive or relapsing weakness affecting proximal and distal muscles. Against this background the review describes the short-term responses to corticosteroids, intravenous immunoglobulin (IVIg) and plasma exchange that have been confirmed in randomised trials. In the absence of better evidence about long-term efficacy, corticosteroids or IVIg are usually favoured because of convenience. Benefit following introduction of azathioprine, cyclophosphamide, cyclosporin, other immunosuppressive agents, and interferon-beta and -alpha has been reported but randomised trials are needed to confirm these benefits. In patients with pure motor CIDP and multifocal motor neuropathy, corticosteroids may cause worsening and IVIg is more likely to be effective. General measures to rehabilitate patients and manage symptoms, including foot drop, weak hands, fatigue and pain, are important.

show abstract

Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Hughes

2003

Drugs

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Management of Chronic Peripheral Neuropathy

Cited by 1 publication

References 63 publications

Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Contact Info

Product

Resources

About