Management of Chronic Strongyloidiasis in Immigrants and Refugees: Is Serologic Testing Useful?

Biggs, Beverley‐Ann; Caruana, Sonia R.; Mihrshahi, Seema; Jolley, Damien; Leydon, Jennie; Chea, Ley; Nuon, Sophy

doi:10.4269/ajtmh.2009.80.788

Cited by 75 publications

(63 citation statements)

References 24 publications

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“…Various polymerase chain reaction methods showed better sensitivity, but have lower sensitivity as burden of larvae decreases. 16 There are proposals for follow-up of antibody level after treatment, 17,18 however further research is needed to assess the value of serology as a marker of eradication.…”

Section: Discussionmentioning

confidence: 99%

Five Cases of Recurrent Meningitis Associated with Chronic Strongyloidiasis

Shimasaki¹,

Chung²,

Shiiki³

2015

The American Society of Tropical Medicine and Hygiene

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Abstract. Although meningitis secondary to chronic strongyloidiasis is a rare complication, it is associated with a high mortality rate. Recurrent meningitis can occur if the underlying parasitic infection is left untreated. We report five cases of recurrent meningitis related to chronic strongyloidiasis that were associated with human T-lymphotropic virus type 1 (HTLV-1) infection. Common causative organisms are Escherichia coli, Streptococcus bovis, and Klebsiella pneumonia. One patient died during the second episode of meningitis. Three patients showed significant gastrointestinal and respiratory symptoms before developing headache and fever. In four cases, patients developed multiple recurrences even with the treatment of thiabendazol. Ivermectin seems to be a better agent compared with thiabendazol to achieve eradication of strongyloidiasis.

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Section: Discussionmentioning

confidence: 99%

Five Cases of Recurrent Meningitis Associated with Chronic Strongyloidiasis

Shimasaki¹,

Chung²,

Shiiki³

2015

The American Society of Tropical Medicine and Hygiene

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“…However, as there is no gold standard test for comparison, these are estimations only. Serological titres decline with effective treatment over a 12 month period 7,18 . …”

Section: Diagnosismentioning

confidence: 99%

Assessing enteric helminths in refugees, asylum seekers and new migrants

2016

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Currently there are 59.5million people forcibly displaced worldwide as a result of conflict, human rights violations, generalised violence or persecution. Of these, 19.5million are refugees and 1.8million are asylum seekers. Each year Australia accepts 13750 refugees through the offshore Humanitarian program, and in 2016 that number will almost double with the addition of 12000 refugees from Syria and Iraq. Many refugees have complex medical needs and have reached Australia after a difficult journey, often involving time in refugee camps and exposure to traumatic events including physical hardship and illness. Refugees often come from parts of the world where parasitic and tropical infectious diseases are prevalent and untreated. This article provides a review of enteric helminth infections in refugees, including asylum seekers and those from a refugee-like background.

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“…Whilst seroconversion does not always take place in patients with strongyloidiasis, serum levels tend to decrease after effective treatment [9,47,[76][77][78][79][80][81].…”

Section: How To Follow Patients After Treatmentmentioning

confidence: 99%

Advances in the Diagnosis of Human Strongyloidiasis

et al. 2014

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Strongyloidiasis is an intestinal parasitic infection that is particularly relevant in immunosuppressed patients because it can cause severe disseminated disease. This review discusses the recent advances in the diagnosis of strongyloidiasis. We suggest clinical and epidemiologic criteria for the diagnosis and screening of strongyloidiasis, taking into account different epidemiologic contexts. The state of the art of the diagnosis of strongyloidiasis is discussed including parasitologic methods that are commonly used despite having low sensitivity; serology, which has demonstrated better sensitivity (with some exceptions such as travelers or immunosuppressed patients), and molecular biology methods, which have virtually 100 % specificity. Finally, we discuss different strategies to follow up patients after treatment, highlighting the importance of having accurate and reliable follow-up markers when assessing treatment efficacy both in a clinical and research context.

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Management of Chronic Strongyloidiasis in Immigrants and Refugees: Is Serologic Testing Useful?

Cited by 75 publications

References 24 publications

Five Cases of Recurrent Meningitis Associated with Chronic Strongyloidiasis

Five Cases of Recurrent Meningitis Associated with Chronic Strongyloidiasis

Assessing enteric helminths in refugees, asylum seekers and new migrants

Advances in the Diagnosis of Human Strongyloidiasis

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