Management of cranial chondroblastoma in adults; a pooled analysis

Muhammed, Amr; Meshneb, Mostafa; Saro, Hossam; Elnakib, Nahawand; Elnakib, Esraa

doi:10.1016/j.amjoto.2020.102486

Cited by 20 publications

(28 citation statements)

References 57 publications

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“…In addition to chemical (phenol), electrocautery or cryosurgery can be used as adjuvant treatment for CB patients[ 30 ]. Whereas surgery is the only effective treatment for cranial CB, the probability of recurrence is greatly increased if residual lesions are present after surgery in patients with cranial CB[ 31 ]. Spinal CB has a higher recurrence rate compared to CB occurring in the long bones, and the growth of spinal CB is more aggressive[ 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Zheng¹,

Niu²,

Wang³

et al. 2021

WJCC

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BACKGROUND Chondroblastoma (CB) is an intermediate tumor of cartilage origin. CB involving the sacrum is a very rare pathology. CASE SUMMARY A 17-year-old male with sacral CB was diagnosed as CB during the first surgery, and 18 mo later, the tumor recurred and a second surgery was performed with the same pathology result of CB. CONCLUSION We recommend complete removal of the tumor in a timely manner, provided that surgical conditions are met. At the same time, other diseases should be carefully differentiated in terms of imaging or pathological features so as to avoid erroneous diagnostic conclusions.

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Section: Discussionmentioning

confidence: 99%

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Zheng¹,

Niu²,

Wang³

et al. 2021

WJCC

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“…Craniofacial chondroblastomas are uncommon, accounting for 2–7% of all chondroblastomas. [ 1 , 23 , 24 ] The most common location in the head and neck region is the skull base, with a predilection for the squamous portion of the temporal bone adjacent to the temporomandibular joint. The other less common sites include mandibular condyle [ Figure 4 ], paranasal sinuses, and maxilla.…”

Section: Benign Cartilaginous Tumors and Tumor-like Lesionsmentioning

confidence: 99%

“…[ 29 , 30 ] Intratumoral cystic degeneration or secondary aneurysmal bone cysts occur frequently in up to one third of these tumors. [ 1 , 23 ] Although the tumors are locally aggressive, distant metastasis is rare. Surgical resection with complete tumor removal is the standard treatment.…”

Section: Benign Cartilaginous Tumors and Tumor-like Lesionsmentioning

confidence: 99%

Imaging features of cartilaginous tumors of the head and neck

Wangaryattawanich

Agarwal

Rath

2021

JCIS

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There is a wide spectrum of head and neck cartilaginous lesions which include both neoplastic and nonneoplastic processes. Cartilaginous tumors of the head and neck are uncommon, posing a diagnostic challenge. Benign cartilaginous tumors that may occur in the head and neck include chondroma, chondroblastoma, chondromyxoid fibroma, osteochondroma, and synovial chondromatosis. Chondromesenchymal hamartoma is a rare non-neoplastic cartilaginous lesion that is included for the 1first time in the new WHO classification and radiologically can mimic a tumor. Malignant cartilaginous tumors include chondrosarcoma and chondroid variant of chordoma. Characteristic tumor locations, internal chondroid matrix calcification, and typical T2 hyperintense signal secondary to high-water content within the extracellular matrix of the hyaline cartilage are useful imaging features that narrow the differential diagnosis and help in diagnosing these diseases. This article presents a narrative review of the anatomy of the head and neck cartilaginous structures, discusses the current knowledge and imaging spectrum of benign and malignant cartilaginous tumors and tumor-like lesions of the head and neck.

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“…This makes the prognostic factors and risk factors appear unclear. A large body of literature reports that different surgical approaches have an important impact on postoperative recurrence [5,6], and even for cranial CB, surgery is simply the only treatment modality [6]. In a study of CB of the spine, the recurrence rate was 100% even for marginally tumor-free curettage, while patients undergoing total en bloc spondylectomy had no recurrence during follow-up [5].…”

Section: Dear Editormentioning

confidence: 99%

“…Finally, when the authors performed a univariate Kaplan-Meier curve by log-rank test, they divided the age into high and low groups using 14 years as the cutoff point, which may make some prognostic factors inaccurate. Previous studies have found that the age of prevalence varies in different sites of CB, and the prognosis of patients differs between different age groups, for example, the mean age of patients with cranial and spinal CB is greater than that of patients with long-bone CB [5,6]; among patients with non-long-bone CB, the prognosis of older patients is significantly better than that of patients with younger CB age [8], so we suggest that the authors use the X-tile software for determining the threshold value of LRFS, i.e., the point corresponding to the minimum P value of the corrected log-rank test [9], a value that can provide valuable guidance for clinical treatment and also help in the clinical management of patients in different age groups.…”

Section: Dear Editormentioning

confidence: 99%

Letter to the Editor concerning the article “Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration”

Zheng

Niu

et al. 2021

World J Surg Onc

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The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article “Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration,” and to further explore some of the factors that may affect the clinical prognosis of chondroblastoma patients. We also suggest future prospective controlled studies with large samples to improve the limitations encountered by Outani et al. (World J Surg Oncol. 18(1):47, 2020) due to insufficient statistical power of variables and lack of controls.

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Management of cranial chondroblastoma in adults; a pooled analysis

Cited by 20 publications

References 57 publications

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Imaging features of cartilaginous tumors of the head and neck

Letter to the Editor concerning the article “Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration”

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