Management of Craniofacial Chondroid Tumors

Cherekaev, V A; Golbin, Denis A.; Gasparyan, T. G.; Шишкина, Л. В.; Tsukanova, Tatiana V.

doi:10.1097/scs.0000000000001307

Cited by 11 publications

(5 citation statements)

References 105 publications

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“…Since cranial chondromas have slow-growing nature, these tumors may have a long asymptomatic period [22]. In many cases, they have reached an advanced tumor size at the time of diagnosis [4,11,19].…”

Section: Discussionmentioning

confidence: 99%

An Intracerebral Type of Cranial Chondroma

Kim

2020

Brain Tumor Res Treat

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The vast majority of intracranial chondromas are located in the base of the cranium. Their presentation as an intracerebral neoplasm is considered to be extremely rare. A previously healthy 45-year-old man experienced recurrent seizure attacks over a period of 6 months. Imaging studies of the brain revealed an ovoid and calcified mass which involve the cortex in the left frontal lobe. Intraoperatively, the mass had no adhesion to the dura and arachnoid membrane. The tumor was completely removed and the final diagnosis was intracerebral chondroma. The patient remained free of disease over the period of 18-years follow-up. This communication adds an unusual case to the literature on the chondroma that expressed in the form of an intra-axial space-occupying lesion in the frontal lobe.

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Section: Discussionmentioning

confidence: 99%

An Intracerebral Type of Cranial Chondroma

Kim

2020

Brain Tumor Res Treat

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“…On pathological examination, S100 and vimentin positive, epithelial markers such as EMA and cytokeratin are negative (2). Surgical resection is the mainstay in treatment of cranial chondroid tumors (1,4,7) and postoperative adjuvant radiation may reduce mortality (1,4,7,10). But for low grade chondrosarcomas, to determine the role of adjuvant therapy, investigations must be performed (1).…”

Section: Discussionmentioning

confidence: 99%

“…Differential diagnosis includes small blue round cell tumors, small cell osteosarcoma. Surgical resection and irradiation is mainstay of treatment (4). Because of the rarity of intracranial chondrosarcomas, the role of chemotherapy is not well defined.…”

Section: Introductionmentioning

confidence: 99%

Intracranial Mesenchymal Chondrosarcoma: A Case Report

Durnalı¹,

Yükrük²,

Kandemir³

et al. 2016

Acta Oncol Tur.

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ÖZET:İntrakranial Kondrosarkomlar çok nadir görülen malign tümörlerdir, intrakranial tümörlerin sadece %15'ini oluştururlar. Bu tümörlerin tedavisinde, cerrahi rezeksiyon ve adjuvan radyoterapi temel yaklaşımlardır. Kemoterapinin rolü iyi tanımlanmamıştır. Biz burada intrakranial mezenkimal kondrosarkom tanılı 26 yaşında erkek hastayı sunduk. Anahtar Kelimeler: İntrakranial, Kemoterapi, Mezenkimal kondrosarkom, Tedavi ABSTRACT:Intracranial chondrosarcomas are very rare malignant tumors, account for only 0.15% of all intracranial tumors. Surgical resection and adjuvant radiotherapy are main approaches of treatment in the treatment of these tumors. The role of chemotherapy is not well defined. We presented a 26 year-old-man diagnosed with intracranial mesenchymal chondrosarcoma.

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“…Тотальне видалення злоякісних краніофаціальних пухлин, у тому числі з інтраорбітальним поширенням, збільшує виживаність і нерецедивний перебіг [11,12,13,14,15,16]. Радикальність видалення інвазивних пухлин орбіти, згідно з нашим дослідженням, чітко залежала від ступеня проростання орбіти.…”

Section: обговоренняunclassified

Surgical treatment and survival of patients with invasive orbital tumors

Паламар,

Гук,

Давиденко

et al. 2023

Oftalmol Zh

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Background: Intraorbital tumor invasion is not uncommon among craniofacial tumors, and is seen in 27% of cases. Craniofacial malignancies account for 3% of all head and neck tumors. Malignant tumors are more common than benign and comprise about 73% of all craniofacial tumors with intraorbital invasion. Their growth is aggressive and invasive, leading to early postoperative recurrence. The survival of patients with malignant craniofacial tumors depends largely on orbital invasion, and patients demonstrating orbital invasion had a 40% survival rate, while patients without had a survival rate of 72%. Patients with total resection of craniofacial tumors (including those with intraorbital extensions) show higher non-recurrence and survival rates than patients without total resection. Orbital exenteration does not provide patients with better survival rates and worsened the quality of life. Purpose: To assess the outcomes of surgical treatment for, and the survival of patients with, malignant craniofacial tumors growing into the orbit. Material and Methods: We reviewed the outcomes of surgical treatment for, and the survival of 94 patients with, malignant craniofacial tumors growing into the orbit. Results: Destruction of the bony orbital wall only (without periorbital adhesion), was seen in 27/94 cases (28.7%), whereas periorbital invasion, in 67/94 cases (71.3%). The tumor was excised completely with visually clear margins in all cases. Patient survival was affected by the degree of orbital invasion. The recurrence rate after surgery for malignant craniofacial tumors growing into the orbit was 44.7% (40/94 patients). Ten patients had a local intraorbital recurrence after surgery for malignant craniofacial tumors growing into the orbit. Conclusion: Periorbital invasion was seen in 71.3% of patients with malignant craniofacial tumors. There was no significant difference in the survival of patients with malignant craniofacial tumors of different histology. Orbital exenteration does not improve survival and recurrence in patients with malignant craniofacial tumors with orbital invasion. In patients with preoperative periorbital invasion and further intraorbital extension, the recurrence rate was more than three-fold higher than in those showing only destruction of the bony orbital wall preoperatively.

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Management of Craniofacial Chondroid Tumors

Abstract: Surgical resection is the mainstay in treatment of both benign and malignant craniofacial tumors, and adjuvant radiation therapy is mandatory in malignant lesions; however, it should be avoided in benign lesions.

Cited by 11 publications

References 105 publications

An Intracerebral Type of Cranial Chondroma

An Intracerebral Type of Cranial Chondroma

Intracranial Mesenchymal Chondrosarcoma: A Case Report

Surgical treatment and survival of patients with invasive orbital tumors

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