2016
DOI: 10.1007/s00431-016-2727-5
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Management of Cushing syndrome in children and adolescents: experience of a single tertiary centre

Abstract: What is Known:-Cushing syndrome is an extremely rare entity in the paediatric and adolescent age groups, so not many cohort studies have been published in this population.-Several tests can be employed to firstly diagnose hypercortisolaemia and secondly, identify the source of origin of it. The efficacy and safety of these tests in children is still uncertain. What is New:-This study includes cases due to the different aetiologies of endogenous hypercortisolaemia (pituitary, adrenal and ectopic hypercortisolae… Show more

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Cited by 34 publications
(30 citation statements)
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“…There was requirement of postoperative hydrocortisone in our patient as she developed postoperative vomiting, headache and weakness, which was tapered and discontinued over a period of one month. This is similar to reports by other authors [18,38] who were able to discontinue hydrocortisone within 1-2 years. The postoperative treatment of CS is challenging with high prevalence of hypertension, increased BMI and visceral fat mass, impaired cognitive functions and decreased quality of life [18,[39][40][41].…”
Section: Bronchial Carcinoids In Childrensupporting
confidence: 92%
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“…There was requirement of postoperative hydrocortisone in our patient as she developed postoperative vomiting, headache and weakness, which was tapered and discontinued over a period of one month. This is similar to reports by other authors [18,38] who were able to discontinue hydrocortisone within 1-2 years. The postoperative treatment of CS is challenging with high prevalence of hypertension, increased BMI and visceral fat mass, impaired cognitive functions and decreased quality of life [18,[39][40][41].…”
Section: Bronchial Carcinoids In Childrensupporting
confidence: 92%
“…When ectopic ACTH secreting lesion is suspected, CT neck, thorax, abdomen and pelvis is done to localise the lesion. Octreotide scan, positron-emission tomography (PET), DOTATE scan and octreotide PET scan can also help in identification of lesion [11,18]. In our patient CT thorax with using 0.5 cm cuts identified lesion of 1.5 cm in apical segment of upper lobe of right lung, which was the source of ectopic ACTH secretion.…”
Section: Discussion 41 Endogenous Cushing's Syndrome (Cs)mentioning
confidence: 65%
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