Introduction: Encouraged by the distinct advantages of minimally invasive plate osteosynthesis technique for treatment of peri-articular fractures of long bones, we have extended the concept for treatment of distal radius fractures. The aim of our study was to evaluate the clinical and functional outcome of MIPO technique for distal radius fractures. Method: Thirty patients with isolated Frkyman's type I to IV fractures of distal radius were treated using minimally invasive approach of proximal vertical and distal transverse incision and fixed with volar locking plate and followed till six months post operatively. Final assessment was done using Mayo wrist scoring system at the end of six months. Results: Based on Mayo wrist scoring system 73% had excellent results and 27% had good results. All patients could return to pre-injury work status by 8 weeks. There were no cases of neuro-vascular injury or joint stiffness and cosmetic acceptance of barely visible scar was very satisfactory. Conclusion: Fixation of extra-articular distal radius fractures and minimally displaced, stable intraarticular fractures by using minimally invasive approach appears to be encouraging, reliable and easily reproducible by all.