Management of Dysphagia in Neurodegenerative Disease

Wu, Jianyu; Burdick, Ryan; Deckelman, Celia; Gustafson, Sara; Yee, Joanne; Rogus-Pulia, Nicole

doi:10.1007/s40136-023-00463-4

Cited by 2 publications

(2 citation statements)

References 118 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Improved understanding of the relationship could contribute to a targeted multidisciplinary approach to the treatment of both swallowing and mental health symptoms. Furthermore, anxiety and depression are prevalent in patients with dementia, and so is swallowing dysfunction 20,21 . Unravelling the relationship between affective disorders and deglutition may bring new insights into this complex population, with currently limited options for swallowing improvement.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Correlations Between Anxiety and/or Depression Diagnoses and Dysphagia Severity

Doruk,

Mocchetti,

Rives

et al. 2023

The Laryngoscope

View full text Add to dashboard Cite

ObjectiveAn increased prevalence of mood and anxiety disorders in patients with dysphagia has been noted previously, but whether dysphagia severity may be exacerbated by anxiety and depression has never been studied before. The purpose of this study is to identify the effect of pre‐existing diagnosis of anxiety and/or depression (anxiety/depression) on the Eating Assessment Tool (EAT‐10), a validated patient‐reported outcome measure for dysphagia. We hypothesized that patients with dysphagia and normal instrumental evaluation have higher EAT‐10 score in the presence of pre‐existing anxiety and depression.MethodsA retrospective chart review was conducted of patients seen at the multi‐disciplinary dysphagia clinic of an urban academic institution. EAT‐10 scores and pre‐existing diagnoses of anxiety/depression were collected at the first visit with laryngologists. The two‐sample t‐test was used to compare mean EAT‐10 scores between the anxiety/depression and no anxiety/depression groups, stratified by swallowing dysfunction etiology.ResultsThe study included 290 consecutive patients seen starting in January 2018. In this cohort, 60 (21%) had pre‐existing anxiety, 49 (17%) depression, and 36 (12%) both. Overall, 59 patients had normal swallowing based on instrumental swallowing testing (flexible endoscopic evaluation of swallowing, videofluoroscopic swallow study, esophagram, or esophagoscopy). Among those, mean EAT‐10 score was significantly higher in patients with anxiety and/or depression (n = 30) (14.63, SD = 11.42) compared to those with no anxiety and/or depression (n = 29) (8.93, SD = 6.59) (p = 0.023).ConclusionWhile anxiety/depression may aggravate dysphagia in patients with normal swallowing function, this correlation may not hold in those with objective swallowing dysfunction.Level of Evidence4 Laryngoscope, 2023

show abstract

Section: Discussionmentioning

confidence: 99%

“…Furthermore, anxiety and depression are prevalent in patients with dementia, and so is swallowing dysfunction. 20,21 Unravelling the relationship between affective disorders and deglutition may bring new insights into this complex population, with currently limited options for swallowing improvement.…”

Section: Discussionmentioning

confidence: 99%