Management of Excess Adiposity

Abstract

The adipose tissue is the largest endocrine organ in humans, mainly located beneath the skin (subcutaneous adipose tissue) but also in other areas (e.g., visceral adipose tissue and ectopic adipose tissue). Excess adiposity is defined as the expansion of adipose tissue (e.g., hypertrophy and hyperplasia) leading to overweight/obesity and related comorbidities. Obesity is a major health problem worldwide inflicting high cost to the society. Management of excess adiposity requires multidisciplinary approaches including lifestyle (e.g., diet, exercise, and behavioral change), food supplements, drugs, medical devices, gut microbiome modulation, body contouring, and bariatric surgery. Long-term weight maintenance remains a challenging goal in most cases.

Interactions between COVID-19 infection and diabetes

“…Management of subjects with excess body weight and COVID-19 who require treatment in intensive care units can be challenging (e.g., difficulty for moving, for intubating, and for obtaining diagnostic Frontiers in Endocrinology frontiersin.org imaging) (15). Subjects with overweight or obesity should have weight reduction using appropriate and tools, when indicated (e.g., diet, exercise, behavioral change, drugs, medical devices, gut microbiome modulation, and bariatric surgery) (32)(33)(34)(35)(36)(37).…”