Management of Fournier's Gangrene: Review of 45 Cases

Başoğlu, Mahmut; Özbey, İsa; Atamanalp, Sabri Selçuk; Yıldırgan, M. İlhan; Aydınlı, Bülent; Polat, Özkan; Öztürk, Gürkan; Peker, Kemal; Önbaş, Ömer; Ören, Durkaya

doi:10.1007/s00595-006-3391-6

Cited by 92 publications

(103 citation statements)

References 26 publications

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“…[2] According to the literature, [2,7,44,79,80] E. coli was the most frequently identified microorganism (n=43, 53.75%) in the present report. Due to the rapid progression of necrotizing infection, use of double or triple wide-spectrum antibiotics initially are necessary to bring the infection under control.…”

Section: Ciprofloxacin 40supporting

confidence: 50%

“…[26,27] The previous reports suggested the highest incidence of male patients in the 6th decade of life. [29][30][31][32][33] Even with the lower incidence rates, the disease was found in females and in all age groups of childhood including newborn and infancy periods. [33][34][35][36][37][38][39][40] The results of the present report were in agreement with the literature regarding age and sex.…”

Section: Ciprofloxacin 40mentioning

confidence: 99%

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Experience of 80 Cases with Fournier's Gangrene and 'Trauma' as a Trigger Factor in the Etiopathogenesis

Eskitaşçıoğlu

Özyazgan

Çoruh

et al. 2014

Ulus Travma Acil Cerrahi Derg

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Section: Ciprofloxacin 40supporting

confidence: 50%

Section: Ciprofloxacin 40mentioning

confidence: 99%

Experience of 80 Cases with Fournier's Gangrene and 'Trauma' as a Trigger Factor in the Etiopathogenesis

Eskitaşçıoğlu

Özyazgan

Çoruh

et al. 2014

Ulus Travma Acil Cerrahi Derg

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“…[4,15,17] DM was the most common comorbidity associated with FG, and it was present in 50% (24-72%) of the patients at the time of admission. [2,7,8,10,[19][20][21][22] Tissue ischemia resulting from the involvement of small vessels has been accounted for increased tendency of diabetics to FG. On the other hand, multifactorial immunologic system dysfunction in diabetics might have caused increased mortality.…”

Section: Discussionmentioning

confidence: 99%

Overview of different scoring systems in Fournier’s Gangrene and assessment of prognostic factors

Doluoğlu

Karagöz

Kılınç

et al. 2016

Turkish Journal of Urology

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Objective: In this study we aimed to evaluate prognostic factors for the survival of patients with Fournier's gangrene (FG), and overview different validated scoring systems for outcome prediction. Material and methods:We retrospectively analyzed the data of 39 patients treated for FG in our clinic. Data were collected on medical history, symptoms, physical examination findings, vital signs, laboratory parameters at admission and at the end of treatment, timing and extent of surgical debridement, and the antibiotic treatment used. The Fournier's Gangrene Severity Index (FGSI) and Charlson Comorbidity Index (CCI) were used to predict outcome. The data were analyzed in relation with the survival of the patients. Mann-Whitney U test, chi -square test, Wilcoxon signed rank test, and Cox regression analysis were used for the statistical analysis.Results: Of 39 patients analyzed, 8 (20.5%) died and 31 (79.5%) survived. The median FGSI score on admission was 2 (0-9) for the survivors and 6 (2-14) for the non-survivors (p=0.004). The median CCI scores of the survivors and non-survivors were 2 (0-10) and 6.5 (5-11), respectively (p=0.001). Except for urea, albumin and hematocrit levels, no significant differences were found between survivors and non-survivors for other laboratory parameters on admission. Lower albumin levels and advanced age were found to be associated with mortality. Conclusion:High blood urea, low albumin, and low hematocrit levels were associated with poor prognosis. High CCI and FGSI scores could be associated with a poor prognosis in patients with FG.

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“…[4] Since it was first defined, FG remains among the most important emergent diseases in the practice of urologists with its high mortality. [5] With its rapidly progressive nature, necrotizing fasciitis carries the risk of invading unexpectedly large areas of the skin if not treated appropriately and, most importantly, on time. In addition to the systemic effects of the infection itself, exotoxins released from the affected necrotic tissue may result in disturbed hemostasis, septic/toxic shock, and eventually death in some of the cases.…”

Section: Discussionmentioning

confidence: 99%

Factors affecting the number of debridements in Fournier's gangrene: our results in 36 cases

Göktaş¹,

Yıldırım²,

Horuz³

et al. 2012

Ulus Travma Acil Cerrahi Derg

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AMAÇBu çalışmada, tek veya çok sayıda cerrahi debridman gereken Fournier gangreni (FG) hastaları karşılaştırıldı, debridman sayısını etkileyebilecek faktörler araştırıldı. GEREÇ VE YÖNTEMFournier gangreni nedeniyle tedavi edilen 36 hastanın verileri geriye dönük olarak incelendi. Hastalar uygulanan debridman sayısına göre iki gruba ayrıldı (Grup I: tek seans; Grup II: ≥2 seans). Hastalara ait veriler (klinik ve cerrahi veriler, lezyon özellikleri, FG şiddet indeksi, prognoz verileri) gruplar arasında karşılaştırıldı. BULGULARHastaların ortalama yaşı 55,5 idi ve hepsi erkekti. Grup I'de 21, Grup II'de 15 hasta incelendi. Grup II'de ortalama debridman sayısı 2,2 idi. Genel mortalite oranı %11 olarak saptandı (Grup I'de %4,8, Grup II'de %20; p=0,287). Diyabet en sık karşılaşılan komorbidite idi (%44). Hastaneye başvu-ruya kadar geçen süre, başvuru sırasında lezyonun boyutu ve FG şiddet indeksi açısından gruplar arasında fark tespit edilmedi. Grup II'de FG şiddet indeksi skorunun tekrarlanan her operasyon öncesinde anlamlı derecede artış gösterdiği saptandı (p<0,05). SONUÇHer ne kadar tek veya çok sayıda debridman uygulanan hastalar arasında debridman sayısını etkileyebilecek anlamlı fark saptanmamışsa da; FG şiddet indeksi, tekrarlanan her debridmanda arttığı tespit edildiği için, ilave debridmanlara karar vermede yardımcı olabilir.

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Management of Fournier's Gangrene: Review of 45 Cases

Abstract: Surgery with extensive debridement of all necrotic tissue is the main stay of treatment.

Cited by 92 publications

References 26 publications

Experience of 80 Cases with Fournier's Gangrene and 'Trauma' as a Trigger Factor in the Etiopathogenesis

Experience of 80 Cases with Fournier's Gangrene and 'Trauma' as a Trigger Factor in the Etiopathogenesis

Overview of different scoring systems in Fournier’s Gangrene and assessment of prognostic factors

Factors affecting the number of debridements in Fournier's gangrene: our results in 36 cases

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