Management of Gallstone Pancreatitis in Pregnancy

Severe Acute Pancreatitis During Pregnancy: Eleven Years Experience from a Surgical Intensive Care Unit

“…The predominance of total biliary cases (61.1%) was in line with the 57-100% noted in earlier studies [1,2,4,18]. However, hypertriglyceridemic pancreatitis was the etiology for 50% of the pregnant SAP patients, which was a much larger proportion compared with the past literature (4-6%) [1,19].…”

“…In a chart review of 101 pancreatitis patients from the United States, the incidence per trimester was 1st, 2nd and 3rd at 24%, 33% and 43%, respectively, which also included chronic pancreatitis and did not distinguish SAP from MAP [1]. The proportion of SAP in this study also fits the rule that frequency increases with gestational age (1st, 2nd, 3rd at 0%, 11.1%, 88.9%, respectively) with a much larger span.…”

“…However, hypertriglyceridemic pancreatitis was the etiology for 50% of the pregnant SAP patients, which was a much larger proportion compared with the past literature (4-6%) [1,19]. Another report in Chinese (from Henan and Guizhou Province) that included 24 SAP patients in the third trimester also confirms a hypertriglyceridemic etiology of 50%.…”

“…Given the current uncertainty, establishing factors that are associated with worse outcomes is necessary to afford clinicians with timely and relatively accurate decision, so that patients could be treated appropriately. However, existing reports are mostly sourced from the obstetrics and gynecology department, where a majority describe mild acute pancreatitis (MAP) [1,4], consequently failing to summarize factors closely related to the more severe consequences of acute pancreatitis. This present study aims to outline the clinical characteristics of severe acute pancreatitis (SAP) during pregnancy and to identify the factors associated with poor outcomes.…”

“…Acute pancreatitis in pregnancy (APIP) is a rare condition estimated to occur in one per 1,500-4,500 pregnancies [1][2][3][4]. APIP has been regarded as a dangerous disease with high maternal death rate and fetal loss rate.…”