Management of gastrointestinal stromal tumors: A 10-year experience of a single surgical department

Janczak, Dariusz; Rać, Jacek; Pawłowski, Wiktor; Dorobisz, T; Ziomek, Agnieszka; Jańczak, Dawid; Leśniak, Michał; Chabowski, Mariusz

doi:10.17219/acem/68718

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The possible reasons for this include: first, with HLS, the surgeon can directly palpate the tumor, bringing about a more accurate position; and second, HLS can better expose the relevant anatomical structures around the tumor to facilitate tissue separation and tumor resection. In addition, HLS has lower requirements for the surgeon's laparoscopic technology, while TLS has higher requirements and a certain learning curve [ 6 , 16 – 20 ]. Consequently, the operation time of HLS was significantly less than that of TLS in our study.…”

Section: Discussionmentioning

confidence: 99%

“…For such patients, there were obvious advantages to HLS. The effect of hand-assisted surgery makes the operation similar to open surgery, where fatal bleeding during the operation can be better controlled [ 20 – 22 ]. Additionally, the surgeon can complete the tumor resection, reduce the probability of conversion to open surgery and preserve normal stomach tissue and gastric function.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hand-assisted laparoscopic resection versus total laparoscopic gastric surgery for primary gastric gastrointestinal stromal tumors (GISTs): an analysis from a high-volume institution

Zhao

Qiu

Zhong³

et al. 2022

BMC Surg

View full text Add to dashboard Cite

Background Laparoscopic resection of gastric gastrointestinal stromal tumors (GISTs) is technically feasible and associated with favorable outcomes. We compared the clinical efficacy of hand-assisted laparoscopic surgery (HLS) and total laparoscopic surgery (TLS) for gastric GISTs. Methods We retrospectively analyzed the clinical data of 69 consecutive patients diagnosed with a gastric GIST in a tertiary referral teaching hospital from December 2016 to December 2020. Surgical outcomes were compared between two groups. Results Fifty-three patients (TLS group: n = 36; HLS group: n = 17) were included. The mean age was 56.9 and 58.1 years in the TLS and HLS groups, respectively. The maximum tumor margin was significantly shorter in the HLS group than in the TLS group (2.3 ± 0.9. vs. 3.0 ± 0.8 cm; P = 0.004). The operative time of the HLS group was significantly shorter than that of the TLS group (70.6 ± 19.1 min vs. 134.4 ± 53.7 min; P < 0.001). The HLS group had less intraoperative blood loss, a shorter time to first flatus, and a shorter time to fluid diet than the TLS group (P < 0.05). No significant difference was found between the groups in the incidence or severity of complications within 30 days after surgery. Recurrence or metastasis occurred in four cases (HLS group; n = 1; TLS group; n = 3). Conclusions This study demonstrated that compared with TLS, HLS for gastric GISTs has the advantages of simpler operation, shorter operative time, and faster postoperative recovery.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Hand-assisted laparoscopic resection versus total laparoscopic gastric surgery for primary gastric gastrointestinal stromal tumors (GISTs): an analysis from a high-volume institution

Zhao

Qiu

Zhong³

et al. 2022

BMC Surg

View full text Add to dashboard Cite

show abstract

Gastrointestinal stromal tumors of the stomach

Uzunoğlu

Tosun

Akıncı

et al. 2021

Nigerian Journal of Clinical Practice

View full text Add to dashboard Cite

Background: Gastrointestinal tract stromal tumors (GIST) are the most common mesenchymal tumors in the gastrointestinal tract (GIS). GISTs may cause significant morbidity and mortality rates. Aim: In this study, it was aimed to evaluate 10 years of gastric GIST cases followed in our hospital, and to analyze the prognostic factors. Subjects and Methods: In this single-center retrospective study, a total of 64 patients who were operated between May 2010 and May 2020 due to gastric GIST tumor were reviewed. Clinical and pathological features, risk classifications, overall survival (OS) and disease-free survival (DFS) were evaluated. Results: According to the risk classification, 18.8% of the patients were in the high-risk group. The overall 5-year OS and DFS rates were 85.7%. The mean OS of the patients was 47.9 SD36.2 months, and the duration of DFS was 45.5 months. Patients with a 5-year OS rate above 5 cm in diameter (P = 0.024), with a mitotic index above 5/50 high power field (HPF) (P = 0.038), and those with a high-risk group (P = 0.011) were significantly lower than the other group. In the correlation analysis, it was found that tumor diameter correlated significantly with OS (P = 0.034; r = -0.317). Tumor diameter and mitotic index were found to be inversely correlated with DFS duration (P = 0.004; r = -0.425 and P = 0.035; r = -0.316, respectively). Conclusion: Our findings showed that in gastric GIST cases, as the primary tumor diameter and mitotic index increase, correlate with survival rates and the mean overall and disease-free survival times decrease.

show abstract

Management of gastrointestinal stromal tumors: A 10-year experience of a single surgical department

Abstract: Background. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive system. The primary location of GISTs is mainly the gastrointestinal system. Clinical symptoms are nonspecific and mainly depend on the location and size of the tumor.

Cited by 2 publications

References 10 publications

Hand-assisted laparoscopic resection versus total laparoscopic gastric surgery for primary gastric gastrointestinal stromal tumors (GISTs): an analysis from a high-volume institution

Hand-assisted laparoscopic resection versus total laparoscopic gastric surgery for primary gastric gastrointestinal stromal tumors (GISTs): an analysis from a high-volume institution

Gastrointestinal stromal tumors of the stomach

Contact Info

Product

Resources

About