Management of Guillain-Barré Syndrome

Gopalakrishna, Kadarapura Nanjundaiah; Ramesh, Venkatapura J.

doi:10.1055/s-0039-1688896

Cited by 3 publications

(4 citation statements)

References 74 publications

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“…It involves a multidisciplinary approach which includes medical and physiotherapy managements [19] . The medical management usually includes the use of intravenous immunoglobulin (IVIg), corticosteroids, plasmaphoresis, and supportive management [4,[20][21][22] . Physiotherapy management is specific to the individual needs and aims to maximize patient's potentials, quality of life and independence [23] .…”

Section: Diagnosis Management and Prognosis Of Guillain-barré Syndromementioning

confidence: 99%

Physiotherapy Management of Guillain-Barré Syndrome in a Tertiary Hospital in South-South Nigeria: A Case Report.

OTI,

OKONKWO,

AYERITE

et al. 2024

ijmsdh

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Background: Guillain-Barré Syndrome (GBS) is a potentially life-threatening post infectious disease characterized by rapidly progressive, symmetrical weakness of the extremities. It can cause life-threatening complications, particularly if the breathing muscles are affected or if there is dysfunction of the autonomic nervous system. Case Presentation: This is a case report of Physiotherapy management of a 51-year old female patient with Guillain-Barré Syndrome (GBS). Patient was referred from the neurology unit, department of Internal Medicine, University of Port Harcourt Teaching Hospital (UPTH) to the neurology clinic of the physiotherapy department, UPTH as a case GBS after series of investigations. Appropriate physiotherapy intervention was given for a period of 36 weeks after a thorough assessment of the patient. The Guillain-Barre Syndrome Disability Score was used to assess the overall functional status of the patient while the Oxford Muscle Grading Scale was used to assess for muscle strength. The Numerical Pain Rating Scale (NPRS) was used to assess the level of pain in the limbs while the Berge Balance Scale (BBS) was used to assess the patient’s balance. The case report was presented in line with the CARE: Case Report Guideline for case reports. All ethical procedures were followed. Treatment outcome: Treatment outcome revealed that the Guillain-Barré Syndrome Disability Score reduced from 4 to 2 while that of Berg Balance Scale increased from 3 to 42 after 36 weeks of intervention. Pain level on range of motion of the limbs based on the Numerical Pain Rating Scale reduced from 6/10 to 1/10 on the upper limb and from 8/10 to 2/10 on the lower limbs. Conclusion: Physiotherapy is effective in the management of patients with Guillain-Barré Syndrome. Early referral to Physiotherapy is key to pain management, balance control and overall functional status of the patients.

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Section: Diagnosis Management and Prognosis Of Guillain-barré Syndromementioning

confidence: 99%

Physiotherapy Management of Guillain-Barré Syndrome in a Tertiary Hospital in South-South Nigeria: A Case Report.

OTI,

OKONKWO,

AYERITE

et al. 2024

ijmsdh

View full text Add to dashboard Cite

show abstract

“…According to evidences, the plasma exchange followed by IVIg is no more efficient than either treatment alone. Besides IVIg and the plasma exchange, corticosteroids can reduce inflammation, and therefore, the disease progression in GBS patients [15][16][17].…”

Section: Guillain-barre Syndrome Treatmentsmentioning

confidence: 99%

Guillain–Barre syndrome: a prevalent autoimmune disease during the coronavirus disease-2019 pandemic

Ahmadi

Rezaei

Shirazi

et al. 2022

Reviews in Medical Microbiology

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Guillain-Barre syndrome (GBS), the most frequent cause of acute paralytic neuropathy, is an inflammatory polyneuropathy that is autoimmune in nature. Many infectious agents such as Campylobacter jejuni (the most commonly identified bacteria associated with GBS), cytomegalovirus, Epstein-Barr virus, measles virus, influenza A virus, and Mycoplasma pneumonia, as well as enterovirus D68 and Zika virus and noninfectious agents such as vaccines and surgeries have been reported to trigger GBS. Three main variants of GBS include the classic acute inflammatory demyelinating polyneuropathy (AIDP), which is the most common presentation of GBS, Miller Fisher syndrome, and the recently defined axon loss variants (acute motor axonal neuropathy and acute motor and sensory axonal neuropathy). One of the assumptions about the mechanisms of GBS is molecular mimicry, which is a process caused due to the structural resemblance between a microorganism and the host. The original concept of GBS is rooted in molecular mimicry defined as the similarity between the microorganisms' peptide sequences or epitopes and ganglioside sequences or structures. Since the coronavirus disease-2019 outbreak in January 2020 there have been cases of GBS reported. Our review aims at providing an overview of some case reports of the severe acute respiratory syndrome coronavirus-2-related GBS.

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“…The pain mostly located in lower extremity, low back, and back, which is positively associated with the level of CSF; this might due to the fact that protein in CSF stimulates nerve root or inflammation of the nerve root (Merkies & Kieseier, 2016; Yao et al, 2019). In short, clinicians should be aware of level of CSF, when CSF increase with pain and anxiety, gabapentin, carbamazepine, and tricyclic antidepressants are suggested to control the pain but opiates and benzos shall be avoided (Gopalakrishna & Ramesh, 2019).…”

Section: Case Reportmentioning

confidence: 99%

“…The recovery of extremity function especially for severely ill patients is very important because the severity has high correlation with rehabilitation. Approximately 70% of the patients still suffer extremity dysfunction after discharge from the hospital (Gopalakrishna & Ramesh, 2019); thus, continuity care beyond the acute care setting to reduce risk of disability and enhance independency is very important. The nurse practitioner is the key person to provide comprehensive assessment and coordinate the multidisciplinary team to develop individualized mental and physical care.…”

Section: Case Reportmentioning

confidence: 99%

Guillain–Barré syndrome in a heart transplantation recipient

Wei

Liu

Chang

et al. 2020

J Am Assoc Nurse Pract

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A rare case of a heart transplantation recipient with Guillain–Barré syndrome occurred, which was associated with peripheral nervous system damage. Based on a review of epidemiological research, the symptom development process, and diagnostic tools, the authors highlight the extreme rarity of this postinfectious immune disease. After diagnosis, plasma exchange and immunoregulatory therapy should be performed because they result in rapid recovery. If there is delayed diagnosis and treatment, there is a high risk of disability or death. When patients experience acute limb paralysis as the main symptom, nurse practitioners (NPs) should focus on the patient's history, particularly with regard to infectious agents. Closely monitoring the patient to detect respiratory failure and the need for early respiratory intervention can help the patient to avoid the severe complication of permanent brain injury. For NPs, performance of early differential diagnosis is important, especially among patients who have immunosuppressive dependence after transplantation.

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Management of Guillain-Barré Syndrome

Cited by 3 publications

References 74 publications

Physiotherapy Management of Guillain-Barré Syndrome in a Tertiary Hospital in South-South Nigeria: A Case Report.

Physiotherapy Management of Guillain-Barré Syndrome in a Tertiary Hospital in South-South Nigeria: A Case Report.

Guillain–Barre syndrome: a prevalent autoimmune disease during the coronavirus disease-2019 pandemic

Guillain–Barré syndrome in a heart transplantation recipient

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