Management of infants with large, unrepaired ventricular septal defects and respiratory infection requiring mechanical ventilation

Abstract

Corrective cardiac surgery for selected critically ill infants with large ventricular septal defects, severe malnutrition, and pneumonia requiring mechanical ventilation is feasible and should be considered a viable management strategy.

Outcome of Infants with Unrepaired Heart Disease Admitted to the Pediatric Intensive Care Unit: Single-center Developing Country Perspective

“…Bhatt et al. suggested that attempts to resolve preoperative respiratory infection completely would not be possible in the presence of significant increased pulmonary blood flow . Patients with CHD awaiting surgery admitted to the PICU in our cohort had high morbidity and mortality depicting a very high risk in these patients.…”

Outcomes of Infant Cardiac Surgery for Congenital Heart Disease Concomitant With Persistent Pneumonia: A Retrospective Cohort Study

“…These maneuvers could reduce the inflammatory process and shorten ICU stay. 14 In the authors' study, the CPB time was longer in the pneumonia group, likely because the complex congenital defects required additional surgical repair in this group. Values are presented as median with range presented in parentheses.…”

Evaluation of biventricular volume and systolic function of medium to large ventricular septal defect with pulmonary hypertension in infants aged within 1 year old by real-time three-dimensional echocardiography

“…For medium to large size ventricular septal defects, due to the presence of moderate to large left to right shunt in infancy, severe pulmonary hypertension usually occured in the early stage, and it is tended to develop recurrent pneumonia, heart failure and In uence children's growth and development, more seriously even life-threatening [5,6] . For these children pulmonary infection and heart failure that are di cult to control, the longer the course of disease, the more severe the in ammatory injury of lung tissue,and the more di cult the recovery after surgery.…”