Management of musculoskeletal dysfunction in infants

Yao, Dan; Deng, Xingqiang; Wang, Mingguang

doi:10.3892/etm.2016.3226

Cited by 2 publications

(2 citation statements)

References 42 publications

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“…However, it was unclear how to identify this condition in a reliable manner, and hence, no corresponding eligibility criteria were defined. Instead, attempts were made to define variables, potentially indicating a musculoskeletal cause, based on the existing literature [ 11 , 16 , 17 ] and knowledge from an expert panel consisting of two maternal and child health nurses and two chiropractors with experience in the paediatric field.…”

Section: Methodsmentioning

confidence: 99%

“…There were, in fact, large individual differences in the effect on crying time, which emphasises the need to investigate if it is possible to identify certain subgroups of children who benefit more from chiropractic care than others. Chiropractic care is concerned with diagnosis and treatment of mechanical disorders in the musculoskeletal system [ 15 ], and in the existing literature, it is hypothesised that one cause of infantile colic could be pain originating from the musculoskeletal system [ 11 , 16 , 17 ]. Included in the protocol for the primary study, we formulated the hypothesis that subgroups of colicky children with musculoskeletal problems potentially would have a larger effect from chiropractic care than others.…”

Section: Introductionmentioning

confidence: 99%

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Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial

et al. 2021

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Background A recent trial identified large variation in effect of chiropractic care for infantile colic. Thus, identification of possible effect modifiers could potentially enhance the clinical reasoning to select infants with excessive crying for chiropractic care. Therefore, the aim of this study is to identify potential treatment effect modifiers which might influence the effect of chiropractic care for excessive crying in infancy. Methods Design: Prespecified secondary analyses of data from a randomised controlled trial. The analyses are partly confirmative and partly exploratory. Setting: Four chiropractic clinics in Denmark. Participants: Infants aged 2–14 weeks with unexplained excessive crying. Of the 200 infants randomised (1:1), 103 were assigned to a chiropractic care group and 97 to a control group. Intervention: Infants in the intervention group received chiropractic care for 2 weeks, while the control group was not treated. Main analyses: The outcome was change in daily hours of crying. Fifteen baseline variables and 6 general variables were selected as potential effect modifiers, and indices based on these were constructed. Factor analyses, latent class analyses and prognosis were used to construct other potentially modifying variables. Finally, an attempt at defining a new index aiming at optimal prediction of the treatment effect was made. The predictive value for all resulting variables were examined by considering the difference in mean change in crying time between the two treatment groups, stratified by the values of the candidate variables, i.e. interaction analyses. Results None of the predefined items or indices were shown to be useful in identifying colicky infants with potentially larger gain from manual therapy. However, more baseline hours of crying (p = 0.029), short duration of symptoms (p = 0.061) and young age (p = 0.089) were all associated with an increased effect on the outcome of hours of crying. Conclusion Musculoskeletal indicators were not shown to be predictive of an increased benefit for colicky infants from chiropractic treatment. However, increased benefit was associated with early treatment and a high level of baseline crying, suggesting that the most severely affected infants have the greatest potential of benefiting from manual therapy. This finding requires validation by future studies. Trial registration Clinical Trials NCT02595515, registered 2 November 2015.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial

et al. 2021

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The association between infantile postural asymmetry and unsettled behaviour in babies

2017

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Questions remain regarding the construct validity of the infantile postural asymmetry scale. No association between unsettled infant behaviour and infantile postural asymmetry was found in 12- to 16-week-old infants. The influence of sex on the interaction between infantile postural asymmetry and infant behaviour needs further examination. An association between unsettled infant behaviour and infantile postural asymmetry is still unproven. What is known: • Unsettled infant behaviour has a considerable impact on many family situations. • Identifying a definitive cause has been a source of much examination and research. Many different hypotheses have been suggested yet much is still unknown. What is new: • The association between unsettled infant behaviour and infantile postural asymmetry is still unproven. • The need to validate a reliable tool to measure infantile postural asymmetry, with particular focus on cervical spine rotation deficit, is indicated.

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Management of musculoskeletal dysfunction in infants

Cited by 2 publications

References 42 publications

Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial

Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial

The association between infantile postural asymmetry and unsettled behaviour in babies

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