Background and Objectives Granular myringitis is troublesome for
otologist because uncertain etiology and often been overlooked due to
vague clinical symptoms and signs. The ideal treatment is elusive. Our
study was to investigate the clinical characteristics of granular
myringitis and analyzing the effect of the two different strategies,
including carbon dioxide laser (CO2 laser) and caustic agent
cauterization to manage granular myringitis. Study Design: Retrospective
review Subjects and Methods One hundred and thirty patients with
granular myringitis receiving treatment at a single medical center from
July 2009 to January 2018 were enrolled. We retrospectively reviewed the
charts and surgical records. The main two different strategies to manage
focal refractory granular myringitis were analyzed, including carbon
dioxide laser and caustic solution. We also recorded the clinical course
and determine which strategy is better. Results One hundred and thirty
patients with granular myringitis were enrolled. 47/130 (36.1%) had
previous otologic procedures. Frequent ototrrhea is the most common
symptom (66.1%). Posterior-inferior quadrant is the most common site of
involvement (58%). The successful rate of CO2 laser, caustic agent were
94.9% and 79.2%. The recurrence rate was comparable between CO2 laser
and caustic agent. No major complication was found in either individual
group. Conclusion: Otologic procedure may be a predisposing factor of
focal chronic myringitis. Ear drops had poor efficacy compared to other
treatments. It can be apply only on minor and fresh symptom cases. In
this study, we suggest CO2 laser can be the first line treatment,
especially for the troublesome or refractory GM cases, which had the
higher successful rate and less complication comparing to caustic agent
cauterization.