Management of neonatal jaundice in low- and lower-middle-income countries

Mir, Shahryar E.; Geest, Berthe A M van der; Been, Jasper V

doi:10.1136/bmjpo-2018-000408

Cited by 16 publications

(14 citation statements)

References 5 publications

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“…Among the 42 eligible infants, 21 infants were randomized to the experimental group, which included 13 males and eight females with an average birthweight of 3.22 AE 0.420 kg, whereas 21 infants were randomized to the control group, which included 13 males and 8 females with an average birthweight of 3.17 AE 0.23 kg (►Fig. 2). No significant difference was observed between these two groups in the baseline demographic and clinical parameters (p > 0.05; ►Table 1).…”

Section: Resultsmentioning

confidence: 99%

Efficacy of Circumferential Intensive Phototherapy in Treating Neonatal Hyperbilirubinemia: A Pilot Study

et al. 2020

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Objective The present study was aimed at developing a circumferential phototherapy unit using 3M reflective materials in the double-sided phototherapy unit and investigating its efficacy in treating neonatal hyperbilirubinemia. Study Design Forty-two infants with neonatal hyperbilirubinemia were selected from our hospital; they were randomly divided into control (n = 21) and experimental groups (n = 21). The experimental group was treated with the circumferential phototherapy unit, while the control group was treated with an ordinary phototherapy unit. Results No significant differences were noted between the two groups in the levels of transcutaneous bilirubin before phototherapy (p > 0.05). After 12 hours of phototherapy, the value of transcutaneous bilirubin decreased significantly in the experimental group compared with that of the control group (p < 0.05). Additionally, the two groups did not exhibit any significant difference in the side effects (p > 0.05). Conclusion Our results indicated that the circumferential phototherapy unit was more effective than the ordinary phototherapy unit in treating neonatal hyperbilirubinemia. Key Points

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Section: Resultsmentioning

confidence: 99%

Efficacy of Circumferential Intensive Phototherapy in Treating Neonatal Hyperbilirubinemia: A Pilot Study

et al. 2020

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Section: Discussionmentioning

confidence: 99%

“…More than 85% of newborns develop some degree of jaundice during the first days of life (9). The clinical symptoms of neonatal jaundice are primarily shown in the head and face, and then affect the organs of the trunk and limbs due to increased serum levels of bilirubin (4,9). Worldwide, it is estimated that extreme neonatal jaundice affects at least 481.000 late-preterm and term newborn infants annually, resulting in 114.000 deaths and more than 63.000 survivors with moderate or severe long-term disability (9).…”

Section: Discussionmentioning

confidence: 99%

“…The clinical symptoms of neonatal jaundice are primarily shown in the head and face, and then affect the organs of the trunk and limbs due to increased serum levels of bilirubin (4,9). Worldwide, it is estimated that extreme neonatal jaundice affects at least 481.000 late-preterm and term newborn infants annually, resulting in 114.000 deaths and more than 63.000 survivors with moderate or severe long-term disability (9). Neonatal jaundice can be fatal, but the mortality rate can be reduced by instant diagnosis and appropriate treatment (10).…”

Section: Discussionmentioning

confidence: 99%

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Yenidoğan Sarılık Ölçüm Yöntemleri ile Felix von Luschan Deri Rengi Skalasının Karşılaştırılması

Genç¹,

Bucak²,

Almış³

et al. 2021

Turkish Journal of Pediatric Disease

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Objective: This study aimed to compare invasive neonatal jaundice measurement methods (total bilirubin from venous blood, total bilirubin in blood gas, and microcapillary neonatal bilirubin from the heel) with the non-invasive Felix von Luschan skin color scale test. Material and Methods: The study was performed on 110 newborns admitted to the neonatal intensive care unit of Adiyaman University Training and Research Hospital, Turkey, because of jaundice. The non-invasive Felix von Luschan skin color scale test was compared with other, more invasive neonatal jaundice measurement methods. Results: The Felix von Luschan skin color scale test was found to have a significant relationship with other diagnostic methods (p<0.001) and deemed practical for the diagnosis of this disease. Conclusion: The timely diagnosis and management of neonatal jaundice are essential to prevent acute bilirubin encephalopathy and kernicterus. The Felix von Luschan skin color scale test is a non-invasive method that is reliable, fast and inexpensive. This method can be used for the diagnosis of neonatal jaundice.

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“…In low–middle-income settings such as South Asia, fluorescent-based PT devices are dominant due to their affordability. This may, however, lead to overtreatment [ 15 ]. In addition, despite the greater number of features available when using LED PT, the use of this type of PT device is still uncommon, particularly in more rural settings [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

An evaluation of phototherapy device performance in a tertiary health facility

Sampurna

Etika

Utomo

et al. 2020

Heliyon

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Introduction A range of phototherapy devices are commercially available. The American Academy of Pediatrics (2004) recommends routine intensity measurement of phototherapy devices to ensure that babies affected by hyperbilirubinemia receive effective phototherapy. Objective The aims of this study were to calculate the irradiance decay velocity of phototherapy devices used in a tertiary care hospital to evaluate whether current maintenance procedures for phototherapy devices are effective, and to contribute to the improvement of a standardized maintenance procedure in daily practice, thus helping to ensure that all babies affected by hyperbilirubinemia receive prompt treatment. Methods This research represents a prospective observational study conducted at Dr. Soetomo Academic Teaching Hospital in Surabaya, Indonesia from February 2019–July 2019. The intensities of 11 phototherapy devices were measured at specific times using a Bili Blanket Meter II. We calculated the Δ irradiance differences in μW/cm 2 /nm and calculated them as velocity μW/cm 2 /nm/hour of use. Results Among the 11 phototherapy devices included in this study, nine were fluorescent and two were light-emitting diode (LED) machines. The mean (standard deviation) irradiance decay velocity of the fluorescent lamps was 0.02 (±0.03) μW/cm 2 /nm/hour of use, while that of the LED lamps was 0.015 (±0.007) μW/cm 2 /nm/hour of use. The fastest irradiance decay velocity was 0.08 μW/cm 2 /nm/hour of use, while the slowest irradiance decay velocity was <0.01 μW/cm 2 /nm/hour of use, both of which were from fluorescent-based devices. There was one fluorescent-based device that provided an intensity lower than the therapeutic level. Conclusion Irradiance decay occurred in all phototherapy device lamps. It is important to perform routinely intensity measurements, regardless of manufacturer recommendations, to avoid ineffective phototherapy resulting from intensities lower than the required therapeutic levels.

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Management of neonatal jaundice in low- and lower-middle-income countries

Cited by 16 publications

References 5 publications

Efficacy of Circumferential Intensive Phototherapy in Treating Neonatal Hyperbilirubinemia: A Pilot Study

Efficacy of Circumferential Intensive Phototherapy in Treating Neonatal Hyperbilirubinemia: A Pilot Study

Yenidoğan Sarılık Ölçüm Yöntemleri ile Felix von Luschan Deri Rengi Skalasının Karşılaştırılması

An evaluation of phototherapy device performance in a tertiary health facility

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