Management of non-palpable breast lesions detected mammographically

Abstract

A total of 212 consecutive fine-wire localization breast biopsies in 202 patients were performed on impalpable mammographically suspicious lesions. Preoperative fine-needle aspiration cytology was performed on 159 lesions and was valuable in planning the extent of the fine-wire localization biopsy. All 212 target lesions were accurately biopsied during the initial surgery. Overall, 134 lesions were malignant and 78 benign (benign:malignant ratio 1:1.72), with fewer biopsies for benign lesions performed in screened patients (benign:malignant ratio 1:2.43) than in those with symptoms (ratio 1:1). Breast conservation was achieved in 72 patients (80 per cent) with screen-detected in situ or invasive carcinoma and in 19 of 37 presenting via a symptomatic clinic. In 160 of 202 patients (79 per cent) the initial fine-wire localization biopsy was diagnostic and therapeutic.

Combined radioguided occult lesion and sentinel node localization for breast cancer

“…This is an excellent technique but has a reported miss rate ranging from 1 to 10% [26][27][28] and a re-excision rate ranging between 18 and 59%. [29][30][31] Given the limitations of this small sample size, our results of a 4.5% miss rate and a 9.5% re-excision rate for the ROLL technique compare favourably with these results. The needle localization technique also has some technical and logistical disadvantages.…”

Diagnostic Potential and Pitfalls of Ultrasound-guided Fine-Needle Aspiration Cytology for Breast Lesions

“…1,8,9 In nonpalpable lesions, our results revealed the sufficient aspirate rate by USguided FNAC to be 70%. 1,8,9 In nonpalpable lesions, our results revealed the sufficient aspirate rate by USguided FNAC to be 70%.…”

“…1,3,7,9,10,[15][16][17] This variation may arise from the differences in aspiration technique, operator skill, tumor size, or histologic types of tumor. 1,3,7,9,10,[15][16][17] This variation may arise from the differences in aspiration technique, operator skill, tumor size, or histologic types of tumor.…”

“…9,17,19 These variable ranges might be partly due to the heterogeneity of the study populations and the calculation methods. 9,17,19 These variable ranges might be partly due to the heterogeneity of the study populations and the calculation methods.…”

Statistical analysis of diagnostic failure of fine needle aspiration cytology (FNAC) in breast cancer

“…Nonpalpable cancer is one of most dif®cult to lead to accurate diagnosis. Not only the detection but diagnostic technique has yet be clearly de®ned and still on dispute [11,12,14,15].…”