Management of osteosarcoma of the maxilla and mandible

Clinical, therapeutic and prognostic features of osteosarcoma of the jaws – Experience of 36 cases

“…Furthermore, an analysis of the literature comprising 44 cases without radical surgical treatment underlines the latter statement. The rate of local relapses was 73%, eight of nine patients died (LiVolsi, 1977;Mardinger et al, 2001;Okinaka and Takahashi, 1997;Roca et al, 1970;Russ and Jesse, 1980;Yokobayashi and Nakajima, 1978). In the present study, more positive margins and more deaths were seen in patients with disease in the mandible.…”

“…The present study had only two cases of metastasis in the lung (5%). In earlier studies it was assumed that osteosarcoma in the jaws have a lesser grade of differentiation than osteosarcoma of the long bones (Roca et al, 1970;Russ and Jesse, 1980) whereas recent studies report high-grade tumours in 87e90% of osteosarcoma of the jaws (Bertoni et al, 1991;Delgado et al, 1994). However, OSJ shows significantly less metastasis than osteosarcoma of the long bones (Clark et al, 1983;Delgado et al, 1994;Mark et al, 1991) with a preference to local relapse (Batsakis, 1984).…”

Osteosarcoma of the mandible in an aged person

“…In general, these finding were common in the literature,(l-ll, 13-33) but the higher alkaline phosphatase value was not and was found in approximately one-third of the cases. ( 15,20,(26)(27)(28) The tumor was in the mandibular body and in the common region.…”

A case of osteosarcoma of the maxilla - challenges in diagnosis and management

“…Osteosarcomas arising from the maxilla cannot always be resected with sufficient margin. This is reflected by a relatively high local recurrence rate (20). Adjuvant chemotherapy has played an important role in increasing the survival of patients with osteosarcoma of the long bones (4).…”