Management of Pancreatic Diabetes Secondary to Chronic Pancreatitis

Shiratori, Keiko

doi:10.1002/9781119188421.ch62

Cited by 4 publications

(2 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Major shortcomings of a substantial amount of studies are caused by the fact that they do not distinguish (define) particular types of diabetes mellitus, mainly type 2, from others. Notably, "pancreatogenic diabetes mellitus" [87][88][89] is a deceptive term as it comprises a diverse set of aetiologies, including PDAC-associated diabetes mellitus and diabetes mellitus associated with chronic non-malignant diseases of the exocrine pancreas. Hard data on the prevalence of "pancreatogenic diabetes" is scarce due to a lack of research on this issue and the difficulties encountered in classification, possibly causing misdiagnosis and underestimation [90].…”

Section: Diabetes Mellitus and Pancreatic Cancermentioning

confidence: 99%

Diabetes Mellitus in Pancreatic Cancer: A Distinct Approach to Older Subjects with New-Onset Diabetes Mellitus

Bureš

Kohoutová

Škrha

et al. 2023

Cancers

View full text Add to dashboard Cite

Background: Pancreatic ductal adenocarcinoma (PDAC) is associated with a very poor prognosis, with near-identical incidence and mortality. According to the World Health Organization Globocan Database, the estimated number of new cases worldwide will rise by 70% between 2020 and 2040. There are no effective screening methods available so far, even for high-risk individuals. The prognosis of PDAC, even at its early stages, is still mostly unsatisfactory. Impaired glucose metabolism is present in about 3/4 of PDAC cases. Methods: Available literature on pancreatic cancer and diabetes mellitus was reviewed using a PubMed database. Data from a national oncology registry (on PDAC) and information from a registry of healthcare providers (on diabetes mellitus and a number of abdominal ultrasound investigations) were obtained. Results: New-onset diabetes mellitus in subjects older than 60 years should be an incentive for a prompt and detailed investigation to exclude PDAC. Type 2 diabetes mellitus, diabetes mellitus associated with chronic non-malignant diseases of the exocrine pancreas, and PDAC-associated type 3c diabetes mellitus are the most frequent types. Proper differentiation of particular types of new-onset diabetes mellitus is a starting point for a population-based program. An algorithm for subsequent steps of the workup was proposed. Conclusions: The structured, well-differentiated, and elaborately designed approach to the elderly with a new onset of diabetes mellitus could improve the current situation in diagnostics and subsequent poor outcomes of therapy of PDAC.

show abstract

Section: Diabetes Mellitus and Pancreatic Cancermentioning

confidence: 99%

Diabetes Mellitus in Pancreatic Cancer: A Distinct Approach to Older Subjects with New-Onset Diabetes Mellitus

Bureš

Kohoutová

Škrha

et al. 2023

Cancers

View full text Add to dashboard Cite

show abstract

“…Diabetes mellitus resulting from CP is classified as T3cDM, also known as pancreatic diabetes. Approximately 80% of patients with pancreatogenic diabetes have CP [9]. Compared to patients with CP but no diabetes, those with post-pancreatitis diabetes mellitus (PPDM) were predominantly male, had a higher prevalence of alcoholic etiology, and showed increased rates of pancreatic calcifications and exocrine insufficiency [10].…”

Section: Introductionmentioning

confidence: 99%

Chronic Calcific Pancreatitis and Its Association With Secondary Diabetes Mellitus

Bahl,

Hussain,

Upadhyay

et al. 2023

J Endocrinol Metab

View full text Add to dashboard Cite

Chronic calcific pancreatitis (CCP) is an inflammatory illness that impacts the pancreas, causing calcifications and scarring inside the gland. Secondary diabetes, commonly referred to as type 3c diabetes mellitus (T3cDM), is one of the probable problems linked with CCP. T3cDM is a form of diabetes caused by an underlying illness or disorder of the endocrine systems. It is a rare cause of diabetes caused by pancreatic pathology. In the regions of Southeast Asian and India, it accounted for 15-20% of individuals with diabetes. This is a rare case report and review of T3cDM. The patient was admitted with a complaint of hyperglycemia, blood glucose of 405 mg/dL with a glycated hemoglobin (HbA1c) level of 13.7%. Computed tomography evidence revealed CCP with intraductal calculi and dilated pancreatic duct.

show abstract