“…1,2,4,5 However, primary mediastinal goiter, which arises from an ectopic mediastinal goiter, is rare (1%) and, importantly, receives a separate blood supply originating from mediastinal vessels including the internal mammary artery, innominate arteries, and intrathoracic aorta. 2,4,5 Several classifi cation systems have been reported to categorize substernal goiters. One recent system classifi es goiters as grades 1-4 based on their extent of intrathoracic extension 8 and another classifi es them as grades 1-3 based on their anatomical location and the recommended surgical approach (cervical, manubriotomy, or full sternotomy).…”