This experiment was conducted at the laboratory of Seed Technology Sakha Agricultural Research Station, Kafr EL-Sheikh, Egypt, during the period between 2018 and 2019 seasons. The aim of this study was to evaluate the effect of packages types and some treatments on wheat seed during storage. The experiment was designed in factorial experiment in completely randomized design with four replicates. The samples were treated with the recommended dose of malathion, recommended rate of phosphine, the powders and extracts of each of (ficus, camphor, clove), the powder of copper nanoparticles and untreated seed as a control treatment. Treated seed were stored in different packages (Jute, Plastic and Polyethylene) for 18 months. The most important results can be summarized as follows: Increasing storage periods of wheat seed up to 18 months significantly affected storage efficacy, vitality and quality of wheat seed. The best results of storage efficacy of wheat recorded when seed stored in polyethylene packages, followed by seed stored in jute packages and lastly stored in plastic packages. Seed treated with copper nanoparticles were the best in germination percentage, electrical conductivity, acidity, protein percentage, carbohydrate percentage, relative density and 1000-seed weight. While treatment with malathion was the best in acidity, relative density, 1000- seed weight and insect infestation percentage. As for phosphine, it was the best in moisture percentage, insect infestation percentage and weight loss percentage. This study recommended that treated seed with copper nanoparticles before storage and stored it in polyethylene packages under the environmental conditions of the experiment in Sakha, Kafr EL-Sheikh, Egypt.